Effects of oxidation defense system exposure to Benzo(a)pyrene on CYP450 gene expression and EROD activity in Crassostrea gigas and Mytilus coruscus
文献类型： 外文期刊
作者： Li, Lei 1 ; Ping, Xianyin 1 ; Li, Ziniu 1 ; Xv, Guodong 1 ; Wang, Cuihua 1 ; Jiang, Mei 1 ;
作者机构： 1.Chinese Acad Fishery Sci, East China Sea Fisheries Res Inst, Shanghai, Peoples R China
关键词： BaP; oxidation defense; CYP450 gene expression; EROD activity; biomarker
期刊名称：ENVIRONMENTAL POLLUTANTS AND BIOAVAILABILITY （ 影响因子：1.737； 五年影响因子：1.737 ）
ISSN： 2639-5932
年卷期： 2021 年 33 卷 1 期
页码：
收录情况： SCI
摘要： Benzo[a]pyrene (BaP) is widely used as a reference compound when studying the toxicity of Polycyclic aromatic hydrocarbons (PAHs) to natural communities. In this study, 15d after exposure to BaP at the nominal concentrations of 5, 1 and 0.2 mu g/L, liver, gill and mantle tissues of Crassostrea gigas and Mytilus coruscuswere taken for BaP uptake assessment, and Cytochrome P450 (CYP450) gene expression level and 7-ethoxyresorufifififin O-deethylase (EROD) activity testing, respectively. CYP450 gene expression level and EROD activity increased significantly with the increase of BaP exposure concentrations. The Significant correlations between BaP uptake and both CYP450 gene expression level and EROD activity indicates that they can be used as a suitable tools for the study of comprehensive levels of biomarker exposed to PAH. There were significant differences in the measurement results of these tissue antioxidant defenses parameters between different treatments.
- 相关文献
作者其他论文 更多>>
-
The presence of microplastics affects Spiella japonica hatching performance and microbiota colonization
作者：Zhang, Tao;Xu, Jilin;Zhang, Tao;Shi, Huilai;Ping, Hongling;He, Jie;Li, Bin;Chen, Xinya;Sun, Ke;Chen, Jiyi;Chen, Xinxin;Yu, Yebing;Sui, Yanming;Li, Lei
关键词：Microplastics; Sepiella maindroni; hatching performance; 16S rRNA; microflora
-
Comparison genetic diversity and population structure of four Pseudaspius leptocephalus populations in Heilongjiang River Basin based on mitochondrial COI gene
作者：Wei, Haijun;Geng, Longwu;Shang, Xinchi;Li, Lei;Ma, Bo;Zhang, Yuyong;Li, Wang;Xu, Wei;Wei, Haijun;Geng, Longwu;Shang, Xinchi;Xu, Wei
关键词：mitochondrial DNA; Pseudaspius leptocephalus; genetic diversity; population structure; COI
-
Whole-Genome Methylation Sequencing of Large Yellow Croaker (Larimichthys crocea) Liver Under Hypoxia and Acidification Stress
作者：Yue, Yanfeng;Wang, Yabing;Zhang, Bianbian;Zeng, Jiao;Wang, Qian;Wang, Cuihua;Peng, Shiming
关键词：Large yellow croaker; Larimichthys crocea; Hypoxia; Acidification; Liver; Methylation
-
Investigation of physiological energetic response of the thick shell mussel, Mytilus coruscus, to microplastics and low salinity: Potential countermeasures to multi-environmental changes
作者：Sui, Yanming;Xue, Zhiyi;Chen, Shihao;Jiang, Huimin;Zhou, Yang;Lv, Linlan;Liu, Longyu;Cao, Tianqi;Wang, Cuihua;Zhang, Shengmao;Zheng, Liang;Nguyen, Haidang;Sui, Yanming
关键词：Mytilus coruscus; Low salinity; Microplastics; Combined effects; Energy budget
-
Seasonal characteristics of nutrient and nutrient structure in the Yangtze River estuary
作者：Li, Lei;Xv, Guodong;Zheng, Yingjie;Jiang, Mei
关键词：Yangtze River estuary; nutrient; spatial and temporal distribution; trophic structure
-
Sediment Properties and Benthic Fauna Associated with Stock Enhancement and Farming of Marine Bivalve Populations in Xiangshan Bay, China
作者：Ping, Xianyin;Zhang, Hui;Jiang, Yazhou;Ling, Jianzhong;Sun, Peng;Tang, Baojun
关键词：
-
Immunomodulatory effects of the polysaccharide from Sinonovacula constricta on RAW264.7 macrophage cells
作者：Liu, Zhidong;Liu, Zhifang;Lin, Na;Jiang, Mei;Li, Laihao;Zhang, Junjie;Zhao, Qiancheng;Zhong, Wenzhu
关键词：immunomodulatory activity; macrophage; polysaccharide; Sinonovacula constricta
