文献类型： 外文期刊

作者： Zhang Jia-Jun ¹ ; Deng Wei-Heng ² ; Ou Shuo-Jun ¹ ; Wang Zhi-Yuan ¹ ; Cen Jian-Bin ² ; Chen Min-Dan ¹ ; Wang Si-Wei ³ ; Z ¹ ;

作者机构： 1.Guangzhou Customs Technol Ctr, Guangzhou 510623, Peoples R China

2.Guangzhou Inspect & Certificat Grp Co Ltd, Guangzhou 511447, Peoples R China

3.Guangdong Acad Agr Sci, Inst Plant Protect, Guangdong Prov Key Lab High Technol Plant Protect, Guangzhou 510640, Peoples R China

关键词： High performance liquid chromatography-tandem quadrupole-time-of-flight-mass spectrometry; Cereals; Indaziflam; Metabolite

期刊名称：CHINESE JOURNAL OF ANALYTICAL CHEMISTRY （ 影响因子：1.134； 五年影响因子：0.909 ）

ISSN： 0253-3820

年卷期： 2021 年 49 卷 8 期

页码：

收录情况： SCI

摘要： A high performance liquid chromatography-tandem quadrupole-time of flight-mass spectrometry ( HPLC-Q-TOF/MS ) method for determination of residues of indaziflam and its four metabolites (1-fluoroethyl triazinediamine , indaziflam-carboxylic acid , triazine-indanone and indaziflam-olefin) in cereal samples was developed. The samples were extracted by acetonitrile , and the supernatant was collected for purification after salting-out and centrifugation. Under the optimized chromatographic and mass spectrometric conditions , the data were collected by electrospray ionization ( ESI) sources in positive ion mode. The calibration curves of five compounds showed good linearity in concentration range of 2. 0 -200 mu g/L ( R-2 >0. 9987) . The average recoveries were 79. 3% -108. 0% at three spiked levels ( 10 , 20 and 100 mu g/kg) , while the relative standard deviations ( RSD) were 1. 2% -6. 0%. The limits of detection and limits of quantification ranged from 0. 05 to 0. 60 mu g/kg and 0. 15 to 2. 00 mu g/kg, respectively. This method was a simple and efficient method with high sensitivity and precision , and had practical value for the rapid detection of residues of indaziflam and its four metabolites in cereals.