文献类型： 外文期刊

作者： Yang, Zexu ¹ ; Zhao, Sicong ¹ ; Li, Jingfang ² ; Gao, Zhihan ³ ; Liu, Dongrong ¹ ; Xu, Yingying ⁴ ; Guo, Erjun ¹ ;

作者机构： 1.Harbin Univ Sci & Technol, Sch Mat Sci & Chem Engn, Key Lab Adv Mfg & Intelligent Technol, Minist Educ, Harbin 150040, Peoples R China

2.Heilongjiang Univ, Sch Chem & Mat Sci, Key Lab Funct Inorgan Mat Chem, Minist Educ, Harbin 150080, Peoples R China

3.Mudanjiang Med Univ, Sch Life Sci, Mudanjiang 157011, Peoples R China

4.Heilongjiang Acad Agr Sci, Qiqihar Branch, Qiqihar 161006, Peoples R China

关键词： Zn alloys; Nanocrystalline; Corrosion mechanism; Biocompatibility; Antibacterial property

期刊名称：JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T （ 影响因子：6.4； 五年影响因子：6.4 ）

ISSN： 2238-7854

年卷期： 2024 年 28 卷

页码：

收录情况： SCI

摘要： The development of biodegradable Zn alloys with comprehensive performance for biomedical applications is still challenging. Hence, the nanocrystalline Zn-Cu-Sr-Li alloys were prepared by alloying design and multi-pass high-speed hot rolling. The Zn-3Cu-0.2Sr-0.4Li alloy achieved nanoscale microstructures, resulting in high strength and an ideal corrosion rate that is more suitable for tissue repair cycles. Scanning Kelvin probe force microscopy analysis revealed the potential from high to low was ranked as: epsilon phase > SrZn13 phase > Zn grains > beta phase. The nanoscale Zn grains and beta particles formed numerous microcells, enhancing the microgalvanic corrosion effect. The Sr ions could be released more efficiently during the degradation in Li-containing alloys, which endowed the alloys with outstanding biocompatibility. Besides, the synergistic release of Zn ions and Cu ions during alloy degradation endowed the alloy with excellent antimicrobial ability against Staphylococcus aureus (inhibition zone diameter approximate to 7.5 mm). The antimicrobial ability of Zn-3Cu-0.2Sr-0.4Li alloy was superior among the reported biodegradable Zn alloys. These results demonstrated nanocrystalline Zn-Cu-Sr-Li alloys have comprehensive performance and broad application prospects in biodegradable bone implants, providing the experimental and theoretical basis for future research in the biomedical field.