Engineering silk-based biomaterials: Extraction, modification, and reprocessing strategies in biomedical applications
文献类型： 外文期刊
作者： Wang, Zhaoyang 1 ; Chen, Haixia 1 ; Yang, Jing 2 ; Du, Xin 1 ; Zhu, Linbao 1 ; Xu, Xiao 1 ; Sun, Guangdong 1 ; He, Xiuling 1 ;
作者机构： 1.Zhejiang Acad Agr Sci, Inst Sericulture & Tea, Hangzhou 310021, Peoples R China
2.Ningxia Med Univ, Yinchuan 750004, Peoples R China
3.High Tech Organ Fibers Key Lab Sichuan Prov, Chengdu 610037, Peoples R China
关键词： Silk-based biomaterials; Regenerative medicine; Drug delivery; Cosmetics
期刊名称：MATERIALS & DESIGN （ 影响因子：7.9； 五年影响因子：8.9 ）
ISSN： 0264-1275
年卷期： 2025 年 254 卷
页码：
收录情况： SCI
摘要： Natural silk, renowned for its remarkable mechanical properties, biocompatibility, degradability, and scalability in production, has become a promising biomaterial for regenerative medicine. Recent advances in silk chemistry and biomaterials engineering have enabled functional modifications of silk and its derived proteins, introduced novel properties, and broadened their application potential. These innovations address limitations in conventional industrial materials, such as hydrogels, scaffolds, and films, thereby significantly expanding their practical utility. This review presents a comprehensive analysis of the structural characteristics of silk and its derived proteins, focusing on the methods used for their extraction, modification, and reprocessing. Furthermore, it explores the latest developments in silk-based biomaterials across three pivotal domains: regenerative medicine, drug delivery, and cosmetics. Finally, the review discusses current challenges and offers insights into the future prospects of silk-based biomaterials.
- 相关文献
作者其他论文 更多>>
-
MPF Regulates Oocyte and Embryo Development During Parthenogenesis Induction in Silkworm, Bombyx mori
作者：Ma, Chenkai;Xu, Fang;Hu, Chengjie;Yu, Wei;Xu, Xia;Ma, Chenkai;Xu, Fang;Hu, Chengjie;Cui, Chunguang;Du, Xin;Chen, Jine;Zhu, Linbao;Yu, Shaofang;He, Xingjian;Wang, Yongqiang;Xu, Xia
关键词：MPF; enzyme activity; embryo development; parthenogenesis;
Bombyx mori -
Beyond biomedical frontiers: Multidimensional applications of silk and its derived proteins in energy, environment, and agri-food systems
作者：Ma, Huanyan;Pan, Meiliang;Wang, Zhaoyang;Hu, Fengyang;Sun, Guangdong;He, Xiuling;Wang, Zhaoyang;Sun, Guangdong
关键词：
-
Decreased Cdk2 Activity Hindered Embryonic Development and Parthenogenesis Induction in Silkworm, Bombyx mori L.
作者：Hu, Chengjie;Jiang, Yonghou;Ma, Chenkai;Xu, Fang;Yu, Wei;Xu, Xia;Hu, Chengjie;Ma, Chenkai;Xu, Fang;Cui, Chunguang;Du, Xin;Chen, Jine;Zhu, Linbao;Yu, Shaofang;He, Xingjian;Wang, Yongqiang;Xu, Xia
关键词：Cdk2; AUZ454; oocytes; embryo; silkworm
-
PPARs Activity Affects the Hatchability Through Lipid Metabolism Regulation in Silkworm, Bombyx mori L.
作者：Xu, Xia;Cui, Chunguang;Song, Houhui;Wang, Yongqiang;Xu, Xia;Cui, Chunguang;Du, Xin;Chen, Jine;He, Xiuling;Zhu, Linbao;Hu, Chengjie;Xu, Fang;Ma, Chenkai;Yu, Shaofang;He, Xingjian;Wang, Yongqiang
关键词：PPARs activity; lipid metabolism; hatchability;
Bombyx mori L. -
Protein Kinase A Regulates the Cell Cycle to Affect the Induction Rate in the Parthenogenetic Reproduction of the Silkworm, Bombyx mori
作者：Xu, Fang;Yu, Wei;Ma, Chenkai;Hu, Chengjie;Xu, Xia;Xu, Fang;Ma, Chenkai;Hu, Chengjie;Cui, Chunguang;Du, Xin;Chen, Jine;Zhu, Linbao;Yu, Shaofang;He, Xingjian;Wang, Yongqiang;Xu, Xia
关键词：PKA; enzyme activity; cell cycle; parthenogenesis;
Bombyx mori -
Multifunctional gelatin-silk fibroin composite hydrogel for skin wound healing
作者：Chen, Haixia;Zhao, Ayong;Wang, Yongqiang;Chen, Haixia;He, Xiuling;Yang, Lei;Sun, Guangdong;Du, Xin;Xu, Xia;Hu, Fengyang;Wang, Yongqiang
关键词：Copper ions; Vascular endothelial growth factor; Silk hydrogel; Skin wounds; Wound healing; Biomaterials
-
A tough and piezoelectric poly(acrylamide/N,N-dimethylacrylamide) hydrogel-based flexible wearable sensor
作者：Wu, Mingyue;Wang, Guohui;Zhang, Mihan;Li, Jinchao;Wang, Chenglong;Sun, Guangdong;Zheng, Jinhuan;Sun, Guangdong
关键词：
