Effect of yeast Saccharomyces cerevisiae supplementation on serum antioxidant capacity, mucosal sIgA secretions and gut microbial populations in weaned piglets
文献类型: 外文期刊
作者: Zhu Cui 1 ; Wang Li 1 ; Wei Shao-yong 1 ; Chen Zhuang 2 ; Ma Xian-yong 1 ; Zheng Chun-tian 1 ; Jiang Zong-yong 1 ;
作者机构: 1.Guangdong Acad Agr Sci, Minist Agr, Inst Anim Sci, Key Lab Anim Nutr & Feed South China, Guangzhou 510640, Guangdong, Peoples R China
2.Guangdong Acad Agr Sci, Agrobiol Gene Res Ctr, Guangzhou 510640, Guangdong, Peoples R China
3.Guangdong Acad Agr Sci, Agro
关键词: Saccharomyces cerevisiae;antioxidant capacity;sIgA;intestinal health;gut microbiota;weaned piglets
期刊名称:JOURNAL OF INTEGRATIVE AGRICULTURE ( 影响因子:2.848; 五年影响因子:2.979 )
ISSN: 2095-3119
年卷期: 2017 年 16 卷 9 期
页码:
收录情况: SCI
摘要: This study was conducted to determine the effect of different forms of yeasts Saccharomyces cerevisiae supplementation on serum antioxidant capacity, mucosal secretory immunoglobulin A (sIgA) secretions and gut microbial populations in weaned piglets. A total of 96 piglets weaned at 14 d of age were randomly allotted to 4 dietary treatments: (1) basal diet without yeast (Control); (2) basal diet supplemented with 3.00 g kg(-1) live yeast (LY); (3) basal diet supplemented with 2.66 g kg(-1) heat-killed whole yeast (HKY); and (4) basal diet supplemented with 3.00 g kg(-1) superfine yeast powders (SFY). Each treatment had 4 replicates (pens), with 6 piglets per replicate. The experiment lasted for 3 wk. At d 7 and 21 of the experiment, the samples of serum, mucosa and mesenteric lymph node (MLN) from jejunum, and digesta from the ileum and cecum were collected for determinations. Compared with the Control, dietary SFY supplementation increased serum superoxide dismutase (SOD) activity and lysozyme levels at d 7, and jejunum mucosal sIgA secretions at d 21 of the experiment (P<0.05). Dietary LY supplementation increased serum SOD activity and jejunum mucosal sIgA secretions, but decreased serum malondialdehyde (MDA) concentration at d 7 and 21 (P<0.05). Piglets fed diets supplemented with LY and SFY had lower pH values and decreased numbers of Escherichia coil in the ileum and cecum contents at d 21 compared with the Control (P<0.05). Moreover, the ratio of Lactobacilli to E. coli in the ileum and cecum contents was increased by dietary LY and SFY supplementations (P<0.05). Collectively, different forms of yeasts, especially LY and SFY, may modulate body antioxidant capacity and enhance the intestinal immunity by regulation of secretions of mucosal sigA and reduction of pathogenic bacteria colonization, thus improving intestinal health of weaned piglets.
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