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Facile fabrication of graphene oxide loaded with silver nanoparticles as antifungal materials

文献类型: 外文期刊

作者: Cui, Jianghu 1 ; Yang, Yunhua 2 ; Zheng, Mingtao 3 ; Liu, Yingliang 3 ; Xiao, Yong 3 ; Lei, Bingfu 3 ; Chen, Wei 4 ;

作者机构: 1.Guangdong Inst Ecoenvironm & Soil Sci, Guangdong Key Lab Agr Environm Pollut Integrated, Guangzhou 510650, Guangdong, Peoples R China

2.Guangdong Inst Microbiol, State Key Lab Appl Microbiol Southern China, Guangdong Prov Key Lab Microbial Culture Collect, Guangzhou 510070, Guangdong, Peoples R China

3.South China Agr Univ, Dept Appl Chem, Guangzhou 510642, Guangdong, Peoples R China

4.Univ Texas Arlington, Dept Phys, Arlington, TX 76019 USA

关键词: graphene oxide;silver nanoparticles;antifungal;oxidative stress;apoptosis;hemolysis

期刊名称:MATERIALS RESEARCH EXPRESS ( 影响因子:1.62; 五年影响因子:1.618 )

ISSN: 2053-1591

年卷期: 2014 年 1 卷 4 期

页码:

收录情况: SCI

摘要: Graphene oxide loaded silver nanoparticles (GO-Ag) were synthesized using a simple method. Our evidence showed that silver nanoparticles (Ag NPs) were successfully loaded on the surface of graphene oxide sheets. The antifungal property of GO-Ag composites was investigated. The results revealed that the obtained GO-Ag composites exhibit enhanced antifungal property in comparison with that of Ag NPs. The toxicity of GO-Ag and Ag NPs were systematically evaluated. The study of cell viability, lactate dehydrogenase, reactive oxygen species, apoptosis/necrosis and hemolysis revealed that GO-Ag composites have lower cytotoxicity and better blood compatibility than Ag NPs. Therefore, these findings provide nanotoxicological information regarding GO-Ag composites which may be alternative antifungal materials in their application of biomedical fields.

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