文献类型: 外文期刊
作者: Tettamanti, G. 1 ; Cao, Y. 2 ; Feng, Q. 3 ; Grimaldi, A. 1 ; de Eguileor, M. 1 ;
作者机构: 1.Univ Insubria, Dept Biotechnol & Mol Sci, I-21100 Varese, Italy
2.S China Agr Univ, Lab Insect Mol Biol & Biotechnol, Guangdong Prov Key Lab Agroanim Genom & Mol Breed, Coll Anim Sci, Guangzhou 510642, Guangdong, Peoples R China
3.S China Normal Univ, Sch Life Sci, Guangzhou 510631, Guangdong, Peoples R China
关键词: autophagy;Lepidoptera;Bombyx mori;ATG genes;apoptosis
期刊名称:ISJ-INVERTEBRATE SURVIVAL JOURNAL ( 影响因子:1.115; 五年影响因子:1.254 )
ISSN: 1824-307X
年卷期: 2011 年 8 卷 1 期
页码:
收录情况: SCI
摘要: Autophagy is a cellular pathway that leads to the degradation of proteins and organelles. This process is usually involved in the maintenance of cell homeostasis when the organism experiences nutrient starvation, but in holometabolous insects autophagy also intervenes in the demolition of larval tissues and organs during metamorphosis. This review summarizes the current knowledge about autophagy research in Lepidoptera and discusses the use of moths and butterflies as models for studying the roles and regulation of autophagy. It also gives insights into the cooperation between autophagy and apoptosis in cell death events that occur in lepidopteran in vivo and in vitro systems.
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