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Transport of Calcium Ions into Mitochondria

文献类型: 外文期刊

作者: Xu, Zhaolong 1 ; Zhang, Dayong 1 ; He, Xiaolan 1 ; Huang, Yihong 1 ; Shao, Hongbo 1 ;

作者机构: 1.Jiangsu Acad Agr Sci, Inst Agrobiotechnol, Prov Key Lab Agrobiol, Jiangsu Key Lab Bioresources Saline Soils, Nanjing, Jiangsu, Peoples R China

2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai, Peoples R China

关键词: Mitochondria;Channels;Calcium ions uptake;Uniporter

期刊名称:CURRENT GENOMICS ( 影响因子:2.236; 五年影响因子:3.377 )

ISSN: 1389-2029

年卷期: 2016 年 17 卷 3 期

页码:

收录情况: SCI

摘要: To uptake calcium ions of mitochondria is of significant functional connotation for cells, because calcium ions in mitochondria are involved in energy production, regulatory signals transfer, and mitochondrial permeability transition pore opening and even programmed cell death of apoptosis, further playing more roles in plant productivity and quality. Cytoplasmic calcium ions access into outer mitochondrial membrane (OMM) from voltage dependent anion-selective channel (VDAC) and were absorbed into inner mitochondrial membrane (IMM) by mitochondrial calcium uniporter (MCU), rapid mitochondrial calcium uptake (RaM) or mitochondrial ryanodine receptor (mRyR). Although both mitochondria and the mechanisms of calcium transport have been extensively studied, but there are still long-standing or even new challenges. Here we review the history and recent discoveries of the mitochondria calcium ions channel complex involved calcium assimilation, and discuss the role of calcium ions into mitochondria.

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