文献类型： 外文期刊
作者： Li, Li 1 ; Xia, Li-Ru 1 ; Wang, He-Ye 1 ; Bi, Xiao-Dong 2 ;
作者机构： 1.Jiangsu Acad Agr Sci, Inst Facil & Equipment Agr, Nanjing 210014, Jiangsu, Peoples R China
2.Nanjing Univ, Sch Chem & Chem Engn, Key Lab Analyt Chem Life Sci, Nanjing 210093, Jiangsu, Peoples R China
关键词： photopolymerization;porous materials;sensors and actuators
期刊名称：JOURNAL OF APPLIED POLYMER SCIENCE （ 影响因子：3.125； 五年影响因子：2.754 ）
ISSN： 0021-8995
年卷期： 2015 年 132 卷 16 期
页码：
收录情况： SCI
摘要： Bisphenol A based epoxy acrylate (BABEA), a commercial UV-curable material, was introduced as a crosslinker for the fabrication of an epoxy-functionalized monolithic polymer array through UV-initiated copolymerization with glycidyl methacrylate as the functional monomer and poly(ethylene glycol) 200 as the porogen. Scanning electron microscopy images showed that the monolithic poly(bisphenol A based epoxy acrylate-co-glycidyl methacrylate) [poly(BABEA-co-GMA)] exhibited a well-controlled skeletal and well-distributed porous structure. The alpha-fetoprotein (AFP) immunoaffinity monolithic polymer array prepared by the immobilization of AFP on epoxy-functionalized monolithic arrays was used as an immunosensor for chemiluminescent AFP detection. X-ray photoelectron spectroscopy results indicate that the AFP antibody was successfully immobilized on the monolithic poly(BABEA-co-GMA) array. With a noncompetitive immune-response format, the proposed AFP immunoaffinity array was demonstrated as a lowcost, flexible, homogeneous, and stable array for AFP detection. (C) 2014 Wiley Periodicals, Inc.
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