您好，欢迎访问浙江省农业科学院 机构知识库！
浙江省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Beyond natural silk: Bioengineered silk fibroin for bone regeneration

文献类型： 外文期刊

作者： Zhou, Keyu 1 ; Yuan, Tao 3 ; Wang, Supeng 2 ; Hu, Fengyang 1 ; Luo, Li 3 ; Chen, Liang 3 ; Yang, Lei 1 ;

作者机构： 1.Zhejiang Acad Agr Sci, Inst Sericulture & Tea, Hangzhou 310021, Peoples R China

2.Ningxia Med Univ, Yinchuan 750004, Peoples R China

3.Univ Chinese Acad Sci, Wenzhou Inst, Wenzhou 325001, Peoples R China

4.Shanghai Jiao Tong Univ, Sch Nursing, Shanghai 200025, Peoples R China

关键词： Bone-tissue engineering; Silk fibroin; Biomaterial; Tissue repair; Scaffold

期刊名称：MATERIALS TODAY BIO （ 影响因子：10.2； 五年影响因子：10.2 ）

ISSN： 2590-0064

年卷期： 2025 年 33 卷

页码：

收录情况： SCI

摘要： Bone regeneration and repair are among the most challenging clinical challenges to overcome. Despite extensive research on bone-tissue repair and regeneration, it remains difficult to achieve perfect regeneration and repair of bone tissue using the current treatments. One new treatment is bone-tissue engineering (TE), which has attracted attention because of its low invasiveness. Silk fibroin (SF), a high-molecular-weight natural fibrous protein secreted by silkworms and spiders, is an ideal choice for melt electrowriting (MEW) of bone TE scaffolds owing to its superior mechanical properties, controlled biodegradation rate, and high biocompatibility. It contains 18 essential amino acids and is widely used in bone grafting. Their physical and chemical properties may be essential for stem cell growth and differentiation, making them ideal scaffold materials for bone TE. In this review, the three primary components of bone TE and the bone-healing process are presented. With an emphasis on recent advancements and the use of bone TE, both in vitro and in vivo, we examined the use of SF in bone TE from the standpoint of its origin and structure. To offer new concepts and avenues for related research, we have also looked at the possible topics for SF research and the present difficulties.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：浙江省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台