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Edible Filamentous Fungi from the Species Monascus: Early Traditional Fermentations, Modern Molecular Biology, and Future Genomics

文献类型: 外文期刊

作者: Chen, Wanping 1 ; He, Yi 3 ; Zhou, Youxiang 4 ; Shao, Yanchun 3 ; Feng, Yanli 5 ; Li, Mu 1 ; Chen, Fusheng 1 ;

作者机构: 1.Huazhong Agr Univ, Key Lab Environm Correlat Dietol, Wuhan 430070, Hubei Province, Peoples R China

2.Huazhong Agr Univ, Natl Key Lab Agromicrobiol, Wuhan 430070, Hubei Province, Peoples R China

3.Huazhong Agr Univ, Coll Food Sci & Technol, Wuhan 430070, Hubei Province, Peoples R China

4.Hubei Acad Agr Sci, Inst Qual Standard & Testing Technol Agroprod, Wuhan 430070, Hubei Province, Peoples R China

5.Hubei Normal Univ, Coll Life Sci, Huangshi 435000, Hubei Prov

关键词: Monascus fermentation;Monascus genomics;Monascus molecular biology;Monascus spp.;red mold rice;secondary metabolites

期刊名称:COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY ( 影响因子:12.811; 五年影响因子:15.365 )

ISSN: 1541-4337

年卷期: 2015 年 14 卷 5 期

页码:

收录情况: SCI

摘要: Monascus spp. are filamentous fungi famous for their fermented products, especially red mold rice (RMR), a traditional fermented food in East Asian areas with a very long edible history documented back to the Han dynasty (BC 202-AD 220) in China. Nowadays, RMR and its related products involve a very large industry from artisanal traditional fermentations to food companies to medicine manufacturers, which are distributed worldwide. Modern studies have shown that Monascus spp. are able to produce abundant beneficial secondary metabolites, such as monacolins (cholesterol-lowering agents), gamma-amino butyric acid (an antihypertensive substance), dimerumic acid (an antioxidant), and pigments (food-grade colorants), and some strains can also secrete citrinin, a nephrotoxic metabolite. Monascus-related studies have received much attention because of their wide applications. However, to our knowledge, no systematic review on the progress of Monascus research has ever been published. In this review, the progress of research on Monascus is summarized into 3 stages: Monascus fermentation, Monascus molecular biology, and Monascus genomics. This review covers the past history, current status, and future direction of Monascus research, contributing to a comprehensive understanding of Monascus research progress.

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[1]Insights into Monascus biology at the genetic level. Chen, Fusheng,Shao, Yanchun,Chen, Fusheng,Shao, Yanchun,Lei, Ming,Mao, Zejing,Chen, Fusheng,Zhou, Youxiang.

[2]NAD(+)-dependent HDAC inhibitor stimulates Monascus pigment production but inhibit citrinin. Hu, Yan,Mao, Zejing,Chen, Fusheng,Shao, Yanchun,Zhou, Youxiang,Li, Huihui. 2017

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