您好，欢迎访问中国热带农业科学院 机构知识库！
中国热带农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Involvement of Chlamydomonas DNA damage tolerence gene UBC2 in lipid accumulation

文献类型： 外文期刊

作者： Fei, Xiaowen 2 ; Li, Xinhan 1 ; Li, Ping 1 ; Deng, Xiaodong 1 ;

作者机构： 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Minist Agr, Key Lab Trop Crop Biotechnol, Haikou 571101, Peoples R China

2.Hainan Med Coll, Sch Sci, Haikou 571101, Peoples R China

关键词： CrUBC2;Ubiquitin conjugating enzyme;Lys-63 polyubiquitination;DNA damage tolerance;Lipid accumulation;Chlamydomonas reinhardtii

期刊名称：ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS （ 影响因子：4.401； 五年影响因子：5.278 ）

ISSN： 2211-9264

年卷期： 2017 年 22 卷

页码：

收录情况： SCI

摘要： The Lys-63-linked polyubiquitination of target proteins is considered a fundamentally different process from conventional Lys-48-linked polyubiquitination. This process is deemed analogous to other post-translational regulatory processes, such as phosphorylation and sumoylation, which alter target protein activities and are reported to be involved in several cellular processes. In this study, we report that CrUBC2, a yeast and Arabidopsis MMS2/UEV homolog gene in Chlamydomonas reinhardtii, is able to functionally rescue yeast mms2 mutant, leading to increased DNA damage tolerance. The overexpression of the CrUBC2 improves the algal ability to tolerate DNA damage, while silencing CrUBC2 sensitizes cells to DNA damage, indicating that CrUBC2 is involved in DNAdamage response in Chlamydomonas. Moreover, the overexpression of CrUBC2 increases algal cell lipid, while the silencing of CrUBC2 gene decreases lipid content, implying that a protein substrate of CrUBC13-CrUBC2 polyubiquitination is involved in lipid accumulation. (C) 2016 Elsevier B. V. All rights reserved.

  • 相关文献

[1]The function of Rad6 gene in Hevea brasiliensis extends beyond DNA repair. Qin, Bi.

[2]The effects of nutritional restriction on neutral lipid accumulation in Chlamydomonas and Chlorella. Deng, Xiaodong,Fei, Xiaowen,Li, Yajun,Fei, Xiaowen. 2011

[3]Effects of selective medium on lipid accumulation of chlorellas and screening of high lipid mutants through ultraviolet mutagenesis. Deng, Xiaodong,Li, Yajun,Fei, Xiaowen,Fei, Xiaowen. 2011

[4]CrMAPK3 regulates the expression of iron-deficiency-responsive genes in Chlamydomonas reinhardtii. Fei, Xiaowen,Yu, Junmei,Li, Yajun,Deng, Xiaodong. 2017

[5]Optimization of the culture conditions of a Chlamydomonas high oil content ultraviolet mutant CC124-M25 and polymorphism analysis by inter-simple sequence repeat (ISSR). Deng, Xiaodong,Zhou, Yujiao,Li, Yajun,Fei, Xiaowen,Fei, Xiaowen. 2012

[6]Effect of the expression and knockdown of citrate synthase gene on carbon flux during triacylglycerol biosynthesis by green algae Chlamydomonas reinhardtii. Cai, Jiajia,Fei, Xiaowen,Deng, Xiaodong. 2013

[7]The mRNA abundance of pepc2 gene is negatively correlated with oil content in Chlamydomonas reinhardtii. Deng, Xiaodong,Li, Yajun,Fei, Xiaowen,Fei, Xiaowen. 2011

[8]Involvement of phosphatidate phosphatase in the biosynthesis of triacylglycerols in Chlamydomonas reinhardtii. Deng, Xiao-dong,Cai, Jia-jia,Fei, Xiao-wen. 2013

[9]Iron deficiency response gene Femu2 plays a positive role in protecting Chlamydomonas reinhardtii against salt stress. Li, Yajun,Wu, Xiaopeng,Deng, Xiaodong,Fei, Xiaowen.

作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国热带农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台