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Metabolites from the endophytic fungus HP-1 of Chinese eaglewood

文献类型: 外文期刊

作者: Zuo Wen-Jian 1 ; Mn Peng-Fei 1 ; Dong Wen-Hua 1 ; Dai Hao-Fu 1 ; Mei Wen-Li 1 ;

作者机构: 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Biol & Genet Resources Trop Crops, Minist Agr, Haikou 571101, Peoples R China

关键词: Chinese eaglewood;Metabolites;Endophytic fungus;Antibacterial activity;Chaetomium sp.

期刊名称:CHINESE JOURNAL OF NATURAL MEDICINES ( 影响因子:3.0; 五年影响因子:2.869 )

ISSN: 2095-6975

年卷期: 2014 年 12 卷 2 期

页码:

收录情况: SCI

摘要: AIM: To study the chemical constituents from the fermentation of the endophytic fungus HP-1 of Chinese eaglewood. METHODS: The chemical constituents were isolated by column chromatography on silica gel and Sephadex LH-20, and their structures were elucidated on the basis of spectroscopic analysis. RESULTS: Four compounds were isolated and identified as 3 alpha, 3 beta, 10 beta-trimethyl-decahydroazuleno[6, 7]furan-8, 9, 14-triol (1), 4-hydroxyphenylacetic acid (2), 4-hydroxyphenethyl alcohol (3), and 5-hydroxymethyl-2-furancarboxaldehyde (4). CONCLUSION: Compound 1 was a new compound. Compound 2 showed antibacterial activity against Staphylococcus aureus.

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