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Dolabranes from the Chinese Mangrove, Ceriops tagal

文献类型： 外文期刊

作者： Hu, Wei-Min 1 ; Li, Min-Yi 1 ; Li, Jun 1 ; Xiao, Qiang 3 ; Feng, Gang 4 ; Wu, Jun 1 ;

作者机构： 1.Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China

2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China

3.Jiangxi Sci & Technol Normal Univ, Inst Organ Chem, Nanchang 330013, Peoples R China

4.Chinese Acad Trop Agr Sci, Environm & Plant Protect Inst, Danzhou 571737, Peoples R China

期刊名称：JOURNAL OF NATURAL PRODUCTS （ 影响因子：4.05； 五年影响因子：4.603 ）

ISSN： 0163-3864

年卷期： 2010 年 73 卷 10 期

页码：

收录情况： SCI

摘要： Six new dolabranes, named tagalsins P-U (1-6), were isolated from stems and twigs of a Chinese mangrove, Ceriops tagal, along with seven known dolabranes, an abietane, and a pimarane. The structures of these compounds were established on the basis of spectroscopic data or comparison with data in the literature. The relative configurations of tagalsins P and Q (1, 2), two new 15,16-dinor-dolabranes, were confirmed by means of single-crystal X-ray diffraction analysis. This is the first report of 16-nordolabranes and 15,16-dinordolabranes from plants of the Ceriops genus. Tagalsins Q (2), R (3), and U (6) showed moderate antifeedant activity against the third-instar larvae of Brontispa longissima at a concentration of 1 mg/mL. However, none of the new dolabranes exhibited significant activity against human cancer cell lines.

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