Whole-genome resequencing and RNA-seq analysis implicates GPR75 as a potential genetic basis related to retarded growth in South China carp ( Cyprinus carpio rubrofuscus) )
文献类型： 外文期刊
作者： Zhong, Zaixuan 1 ; Fan, Jiajia 1 ; Tian, Yuanyuan 1 ; Lin, Minhui 1 ; Zhu, Huaping 1 ; Ma, Dongmei 1 ;
作者机构： 1.Chinese Acad Fishery Sci, Pearl River Fisheries Res Inst, Guangzhou, Guangdong, Peoples R China
2.Minist Agr & Rural Affairs, Key Lab Trop & Subtrop Fishery Resources Applicat, Guangzhou, Guangdong, Peoples R China
3.Guangdong Prov Key Lab Aquat Anim Immunol & Sustai, Guangzhou, Guangdong, Peoples R China
关键词： Whole-genome resequencing; South China carp; Retarded growth; Gpr75
期刊名称：GENOMICS （ 影响因子：3.0； 五年影响因子：3.3 ）
ISSN： 0888-7543
年卷期： 2024 年 116 卷 5 期
页码：
收录情况： SCI
摘要： The south China carp ( Cyprinus carpio rubrofuscus) ) is an indigenous and important fish species, widely cultured in south China. However, part of individuals experienced retarded growth, the genetic basis of which has yet to be elucidated. In this study, whole-genome resequencing of 35 fast-growing and 35 retarded-growing south China carp were conducted to identify promising genes associated with retarded growth. Twelve candidate SNPs were detected and annotated to the Gpr75 gene, which has been reported to be related with body weight through regulating insulin homeostasis. RNA-seq analysis of muscle suggested that differentially expressed genes were significantly enriched in the insulin signaling pathway. Additionally, the fasting serum insulin level was significantly lower while the blood glucose level was significantly higher in the retarded-growing group. Our preliminary study provides insights into the genetic basis underlying the retarded growth and may facilitate further genetic improvement of south China carp.
- 相关文献
作者其他论文 更多>>
-
Full-Length Transcriptome Sequencing and Comparative Transcriptomics Reveal the Molecular Mechanisms Underlying Gonadal Development in Sleepy Cod (Oxyeleotris lineolata)
作者：Fan, Jiajia;Ma, Dongmei;Zhu, Huaping;Lin, Minghui;Zhong, Zaixuan;Tian, Yuanyuan;Fan, Jiajia;Ma, Dongmei;Zhu, Huaping;Lin, Minghui;Zhong, Zaixuan;Tian, Yuanyuan
关键词：sleepy cod Oxyeleotris lineolata; sexual dimorphism; transcriptome; sex determination; gonadal differentiation
-
A TMT-Based Proteomic Analysis of Osmoregulation in the Gills of Oreochromis mossambicus Exposed to Three Osmotic Stresses
作者：Su, Huanhuan;Ma, Dongmei;Fan, Jiajia;Zhong, Zaixuan;Tian, Yuanyuan;Zhu, Huaping;Su, Huanhuan;Ma, Dongmei;Fan, Jiajia;Zhong, Zaixuan;Tian, Yuanyuan;Zhu, Huaping
关键词：TMT-based proteomics; gills; osmotic stresses;
Oreochromis mossambicus -
Effects of Dietary Astaxanthin on Growth, Coloration, Immunity, and Antioxidant Capacity in Macrobrachium Rosenbergii
作者：Li, Huarong;Yu, Lingyun;Wei, Jie;Bai, Liufu;Su, Qiyao;Hong, Kunhao;Zhou, Qiaoyan;Zhu, Huaping;Wang, Yakun;Li, Huarong;Su, Qiyao;Hong, Kunhao;Bai, Liufu;Zhou, Qiaoyan
关键词：astaxanthin; body color; gene expression; growth performance; immunity; Macrobrachium rosenbergii
-
Isolation and characterization of 48 SNP markers of sleepy cod, Oxyeleotris lineolata by whole-genome resequencing
作者：Fan, Jiajia;Ma, Dongmei;Zhu, Huaping;Lin, Minghui;Su, Huanhuan;Zhong, Zaixuan;Fan, Jiajia;Ma, Dongmei;Zhu, Huaping;Lin, Minghui;Su, Huanhuan;Zhong, Zaixuan
关键词：Oxyeleotris lineolata; SNP; Whole-genome resequencing; Genetic linkage map; Genetic improvement
-
Comparative transcriptome, ultrastructure and histology analyses provide insights into the potential mechanism of growth arrest in south China carp (Cyprinus carpio rubrofuscus)
作者：Zhong, Zaixuan;Fan, Jiajia;Tian, Yuanyuan;Zhu, Huaping;Ma, Dongmei;Zhong, Zaixuan;Fan, Jiajia;Tian, Yuanyuan;Zhu, Huaping;Ma, Dongmei;Zhong, Zaixuan;Fan, Jiajia;Tian, Yuanyuan;Zhu, Huaping;Ma, Dongmei
关键词：South China carp; Growth arrest; RNA-seq; Ultrastructure; Histology
-
Metabolism responses in the intestine of Oreochromis mossambicus exposed to salinity, alkalinity and salt-alkalinity stress using LC-MS/MS-based metabolomics
作者：Su, Huanhuan;Li, Yaya;Su, Huanhuan;Li, Yaya;Ma, Dongmei;Fan, Jiajia;Zhong, Zaixuan;Zhu, Huaping;Zhu, Huaping
关键词：Metabolomics; Intestine; Oreochromis mossambicus; Osmotic stress
-
Metabolism response mechanism in the gill of Oreochromis mossambicus under salinity, alkalinity and saline-alkalinity stresses
作者：Su, Huanhuan;Ma, Dongmei;Fan, Jiajia;Zhong, Zaixuan;Li, Yaya;Zhu, Huaping;Ma, Dongmei;Fan, Jiajia;Zhu, Huaping;Su, Huanhuan;Li, Yaya;Zhu, Huaping
关键词：Metabolism; Oreochromis mossambicus; Osmotic stress; Gill; Osmoregulation
