MoCbp7, a Novel Calcineurin B Subunit-Binding Protein, Is Involved in the Calcium Signaling Pathway and Regulates Fungal Development, Virulence, and ER Homeostasis in Magnaporthe oryzae
文献类型： 外文期刊
作者： Wang, Zi-He 1 ; Shen, Zi-Fang 1 ; Wang, Jing-Yi 1 ; Cai, Ying-Ying 1 ; Li, Lin 2 ; Liao, Jian 1 ; Lu, Jian-Ping 3 ; Zhu, Xue-Ming 2 ; Lin, Fu-Cheng 1 ; Liu, Xiao-Hong 1 ;
作者机构： 1.Zhejiang Univ, Inst Biotechnol, State Key Lab Rice Biol & Breeding, Hangzhou 310058, Peoples R China
2.Zhejiang Acad Agr Sci, Inst Plant Protect & Microbiol, State Key Lab Managing Biot & Chem Treats Qual & S, Hangzhou 310021, Peoples R China
3.Zhejiang Univ, Coll Life Sci, Hangzhou 310058, Peoples R China
关键词： Magnaporthe oryzae; calcium signaling; calcineurin; virulence; endoplasmic reticulum stress
期刊名称：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES （ 影响因子：5.6； 五年影响因子：6.2 ）
ISSN： 1661-6596
年卷期： 2023 年 24 卷 11 期
页码：
收录情况： SCI
摘要： Calcineurin, a key regulator of the calcium signaling pathway, is involved in calcium signal transduction and calcium ion homeostasis. Magnaporthe oryzae is a devastating filamentous phytopathogenic fungus in rice, yet little is known about the function of the calcium signaling system. Here, we identified a novel calcineurin regulatory-subunit-binding protein, MoCbp7, which is highly conserved in filamentous fungi and was found to localize in the cytoplasm. Phenotypic analysis of the MoCBP7 gene deletion mutant (Delta Mocbp7) showed that MoCbp7 influenced the growth, conidiation, appressorium formation, invasive growth, and virulence of M. oryzae. Some calcium-signaling-related genes, such as YVC1, VCX1, and RCN1, are expressed in a calcineurin/MoCbp7-dependent manner. Furthermore, MoCbp7 synergizes with calcineurin to regulate endoplasmic reticulum homeostasis. Our research indicated that M. oryzae may have evolved a new calcium signaling regulatory network to adapt to its environment compared to the fungal model organism Saccharomyces cerevisiae.
- 相关文献
作者其他论文 更多>>
-
A rho-type GTPase activating protein affects the growth and development of Cordyceps cicadae
作者：Li, Xueqian;Zou, Yu;Wang, Hongkai;Shrivastava, Neeraj;Bao, Jiandong;Lin, Fu-Cheng
关键词：Cordyceps cicadae; Rho-type GTPase activating protein; Growth and development; Active components
-
Stimuli-responsive biodegradable silica nanoparticles: From native structure designs to biological applications
作者：Qi, Qianhui;Wang, Wei;Shen, Qian;Geng, Jiaying;An, Weizhen;Wu, Qiong;Yu, Changmin;Shen, Qian;Geng, Jiaying;An, Weizhen;Wu, Qiong;Yu, Changmin;Qi, Qianhui;Yu, Changmin;Wang, Nan;Zhang, Yu;Li, Xue;Li, Lin
关键词：Biodegradation; Silica nanoparticles; Stimuli -responsive; Multiple frameworks; Biological applications
-
Roles of CcDFR and CcOMT9 in the cyanidin biosynthesis and development of Cordyceps cicadae
作者：Zeng, Zixuan;Zou, Yu;Wang, Hongkai;Cai, Weiming;Lin, Fu-Cheng
关键词：Cordyceps cicadae; cyanidin-3-O-glucoside; growth and development; bioactive substance; gene function
-
Genome-Wide Identification and Characterization of Effector Candidates with Conserved Motif in Falciphora oryzae
作者：Dai, Mengdi;Zhu, Xueming;Li, Lin;Lin, Fucheng;Dai, Mengdi;Ye, Ziran;Tan, Xiangfeng;Kong, Dedong;Su, Zhenzhu;Liu, Xiaohong;Lin, Fucheng
关键词：genome-wide; effector; conserved motif; endophyte
-
A key sphingolipid pathway gene, MoDES1, regulates conidiation, virulence and plasma membrane tension in Magnaporthe oryzae
作者：Wang, Lei;Zhang, Xiaozhi;Lin, Fucheng;Zhu, Xueming;Li, Lin;Bao, Jiandong;Lin, Fucheng;Zhu, Xueming;Lin, Fucheng
关键词：Magnaporthe oryzae; MoDES1; Sphingolipid; Pathogenic fungi; Lipid homeostasis; PM tension
-
Csn5 inhibits autophagy by regulating the ubiquitination of Atg6 and Tor to mediate the pathogenicity of Magnaporthe oryzae
作者：Shen, Zi-Fang;Li, Lin;Zhu, Xue-Ming;Lin, Fu-Cheng;Shen, Zi-Fang;Wang, Jing-Yi;Liao, Jian;Zhang, Yun-Ran;Wang, Zi-He;Liu, Xiao-Hong;Lin, Fu-Cheng;Lu, Jian-Ping
关键词：COP9 signalosome; Csn5; Autophagy; Ubiquitination; Pathogenicity; Rice blast fungus
-
SP-141 targets Trs85 to inhibit rice blast fungus infection and functions as a potential broad-spectrum antifungal agent
作者：Wu, Xi-Yu;Cai, Ying-Ying;Liu, Xiao-Hong;Lin, Fu-Cheng;Dong, Bo;Zhu, Xue-Ming;Li, Lin;Xu, Fei;Bao, Jian-Dong;Lin, Fu-Cheng;Dong, Bo;Dong, Bo;Lu, Jian-Ping;Yu, Bin;Cheng, Jing-Li;Wang, Ying
关键词：Magnaporthe oryzae; rice blast; TRAPPIII complex; trs85; fungicide
