MoCbp7, a Novel Calcineurin B Subunit-Binding Protein, Is Involved in the Calcium Signaling Pathway and Regulates Fungal Development, Virulence, and ER Homeostasis in Magnaporthe oryzae
文献类型： 外文期刊
作者： Wang, Zi-He 1 ; Shen, Zi-Fang 1 ; Wang, Jing-Yi 1 ; Cai, Ying-Ying 1 ; Li, Lin 2 ; Liao, Jian 1 ; Lu, Jian-Ping 3 ; Zhu, Xue-Ming 2 ; Lin, Fu-Cheng 1 ; Liu, Xiao-Hong 1 ;
作者机构： 1.Zhejiang Univ, Inst Biotechnol, State Key Lab Rice Biol & Breeding, Hangzhou 310058, Peoples R China
2.Zhejiang Acad Agr Sci, Inst Plant Protect & Microbiol, State Key Lab Managing Biot & Chem Treats Qual & S, Hangzhou 310021, Peoples R China
3.Zhejiang Univ, Coll Life Sci, Hangzhou 310058, Peoples R China
关键词： Magnaporthe oryzae; calcium signaling; calcineurin; virulence; endoplasmic reticulum stress
期刊名称：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES （ 影响因子：5.6； 五年影响因子：6.2 ）
ISSN： 1661-6596
年卷期： 2023 年 24 卷 11 期
页码：
收录情况： SCI
摘要： Calcineurin, a key regulator of the calcium signaling pathway, is involved in calcium signal transduction and calcium ion homeostasis. Magnaporthe oryzae is a devastating filamentous phytopathogenic fungus in rice, yet little is known about the function of the calcium signaling system. Here, we identified a novel calcineurin regulatory-subunit-binding protein, MoCbp7, which is highly conserved in filamentous fungi and was found to localize in the cytoplasm. Phenotypic analysis of the MoCBP7 gene deletion mutant (Delta Mocbp7) showed that MoCbp7 influenced the growth, conidiation, appressorium formation, invasive growth, and virulence of M. oryzae. Some calcium-signaling-related genes, such as YVC1, VCX1, and RCN1, are expressed in a calcineurin/MoCbp7-dependent manner. Furthermore, MoCbp7 synergizes with calcineurin to regulate endoplasmic reticulum homeostasis. Our research indicated that M. oryzae may have evolved a new calcium signaling regulatory network to adapt to its environment compared to the fungal model organism Saccharomyces cerevisiae.
- 相关文献
作者其他论文 更多>>
-
The endosomal-vacuolar transport system acts as a docking platform for the Pmk1 MAP kinase signaling pathway in Magnaporthe oryzae
作者：Wang, Qing;Huang, Zhicheng;Li, Yan;Li, Hui;Lin, Fu-Cheng;Lu, Jianping;Wang, Jing;Cai, Yingying;Wang, Jiaoyu;Lin, Fu-Cheng;Huang, Pengyun;Liu, Xiaohong;Lin, Fu-Cheng
关键词：appressorium; endosome; MAPK; Pmk1; rice blast fungus; signal; ubiquitination; vacuole
-
A multilayered regulatory network mediated by protein phosphatase 4 controls carbon catabolite repression and de-repression in Magnaporthe oryzae
作者：Huang, Zhicheng;Wang, Qing;Li, Yan;Li, Hui;Lin, Fu-Cheng;Lu, Jianping;Huang, Pengyun;Liao, Jian;Liu, Xiaohong;Lin, Fu-Cheng;Wang, Jing;Cai, Yingying;Wang, Jiaoyu;Lin, Fu-Cheng
关键词：
-
MoSec13 combined with MoGcn5b modulates MoAtg8 acetylation and regulates autophagy in Magnaporthe oryzae
作者：Qian, Hui;Wu, Ming-Hua;Zhao, Wen-Hui;Lin, Fu-Cheng;Liu, Xiao-Hong;Zhu, Xue-Ming;Lin, Fu-Cheng;Zhu, Xue-Ming;Lin, Fu-Cheng;Sun, Li-Xiao;Lu, Jian-Ping;Klionsky, Daniel J.
关键词：Autophagy; Gcn5b;
Magnaporthe oryzae ; Sec13; TORC2 -
The whole genome sequence of Cordyceps cicadae - an edible and potential medicinal fungus
作者：Liu, Yuwei;Li, Xueqian;Meng, Yiqi;Zhou, Wei;Lin, Fu-Cheng;Wang, Hongkai;Lin, Fu-Cheng;Wu, Yifan;Jin, Yuting;Ma, Xiaotong;Tan, Yuchong
关键词：
Cordyceps cicadae ; Whole genome; Hi-C sequencing -
Integrated Transcriptomic and Metabolomic Analysis Reveals the Regulation Network of CEBiP in Rice Defense Against Magnaporthe oryzae
作者：Zheng, Qi;Bao, Jiandong;Li, Lin;Shen, Zifang;Wang, Jiaoyu;Daskalov, Asen;Zhu, Xueming;Lin, Fucheng;Li, Lin;Lin, Fucheng;Daskalov, Asen
关键词：
Magnaporthe oryzae ; rice blast disease; CEBiP; pattern recognition receptor; transcriptomics; metabolomics -
FK506 Targets MoFpr1 to Modulate Autophagy and Ubiquitination, Inhibiting the Pathogenicity of Magnaporthe oryzae
作者：Zhao, Wen-Hui;Yan, Jiong-Yi;Xie, Ke-Xin;Luo, Xi-Chun;Liao, Jian;An, Chun-Yue;Liu, Xiao-Hong;Yan, Jiong-Yi;Liang, Shuang;Zhu, Xue-Ming;Lin, Fu-Cheng;Wu, Xi-Yu;Qian, Hui;Lu, Jian-Ping;Khan, Irshad Ali
关键词：FK506; X-ray crystallography; riceblast; broad-spectrum antifungal activity
-
Nuclear basket nucleoporin MoNup50 is essential for fungal development, pathogenicity, and autophagy in Magnaporthe oryzae
作者：Cai, Ying-Ying;Zhu, Xue-Ming;Noman, Muhammad;Wang, Jing;Hao, Zhong-Na;Wang, Yan-Li;Li, Lin;Wang, Jiao-Yu;Lin, Fu-Cheng;Liu, Xiao-Hong;Lin, Fu-Cheng;Lu, Jian-Ping
关键词：Rice blast fungus; Virulence; Atg7; Nuclear pore complex
