Two new 2-(2-phenethyl)chromone derivatives from agarwood of Aquilaria walla and their cytotoxicity
文献类型： 外文期刊
第一作者： Wang, Yue-Yue
作者： Wang, Yue-Yue;Wang, Yue-Yue;Wang, Hao;Mi, Cheng-Neng;Li, Wei;Gai, Cui-Juan;Yuan, Jing-Zhe;Mei, Wen-Li;Dai, Hao-Fu;Xu, Shi-Tao
作者机构： Hainan Univ, Coll Trop Agr, Haikou 570228, Hainan, Peoples R China;Chinese Acad Trop Agr Sci, Hainan Engn Res Ctr Agarwood, Minist Agr, Key Lab Biol & Genet Resources Trop Crops, Haikou 571101, Hainan, Peoples R China;Hainan Univ, Coll Hort, Haikou 570228, Hainan, Peoples R China
关键词： Aquilaria walla; Agarwood; Dimeric 2-(2-phenethyl)chromone; Flavonoid-2-(2-phenethyl)chromone; Cytotoxicity
期刊名称：PHYTOCHEMISTRY LETTERS （ 2019影响因子：1.459； 五年影响因子：1.601 ）
ISSN： 1874-3900
年卷期： 2021 年 42 卷
收录情况： SCI
摘要： Two new 2-(2-phenethyl)chromone derivatives were isolated from agarwood of Aquilaria walla, including a dimeric 2-(2-phenethyl)chromone (1) and a flavonoid-2-(2-phenethyl)chromone (2). Their structures were established based on spectroscopic methods including HRESIMS, 1D, and 2D NMR. Compounds 1 and 2 showed cytotoxic activity against five human cancer cell lines with IC50 values ranging from 4.96?44.34 ?M.
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