Six New Phragmalin Limonoids from the Stems of Chukrasia tabularis A. Juss

文献类型： 外文期刊

第一作者： Wang, Yan-Cui

作者： Wang, Yan-Cui;Kong, Fan-Dong;Wang, Hao;Mei, Wen-Li;Zhao, You-Xing;Dai, Hao-Fu;Liu, Shou-Bai

作者机构：

关键词： Chukrasia tabularis A; Juss; Meliaceae; phragmalin limonoid; -glucosidase inhibition activity; acetylcholinesterase inhibitory activity

期刊名称：MOLECULES （ 影响因子：4.411； 五年影响因子：4.587 ）

ISSN： 1420-3049

年卷期： 2018 年 23 卷 11 期

页码：

收录情况： SCI

摘要： Six new phragmalin limonoids, named moluccensin Z1 (1), moluccensin Z2 (2), carapanolide Y (3), tabulalin N (4), chukvelutilide A1 (5), and velutinasin J (6), as well as two known compounds, chukvelutilide A (7) and velutinasin D (8) were isolated from the stems of Chukrasia tabularis A. Juss. The structures of the new compounds 1-6 were confirmed by spectroscopic methods, including IR and HRESIMS, as well as 1D and 2D NMR, and by comparisons with the data of known analogues. All compounds were tested for -glucosidase and acetylcholinesterase inhibitory activities. However, none of the compounds was active against -glucosidase and acetylcholinesterase in vitro.

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