Three new 2-(2-phenylethyl)chromones from Chong-lou' agarwood of Aquilaria sinensis

文献类型: 外文期刊

第一作者: Su, Xin

作者: Su, Xin;Cai, Cai-Hong;Dong, Wen-Hua;Gai, Cui-Juan;Wang, Ya-Li;Mei, Wen-Li;Dai, Hao-Fu;Chen, Hui-Qin;Su, Xin;Cai, Cai-Hong;Dong, Wen-Hua;Gai, Cui-Juan;Wang, Ya-Li;Mei, Wen-Li;Dai, Hao-Fu;Chen, Hui-Qin;Su, Xin;Xu, Xing-Lian;Dai, Hao-Fu

作者机构:

关键词: Chong-lou' agarwood; Aquilaria sinensis; 2-(2-phenylethyl)chromones; Cytotoxicity

期刊名称:PHYTOCHEMISTRY LETTERS ( 影响因子:1.873; 五年影响因子:1.875 )

ISSN: 1874-3900

年卷期: 2022 年 51 卷

页码:

收录情况: SCI

摘要: Three new 2-(2-phenylethyl)chromones (1, 2 and 3), together with four known analogues 4-7 were isolated from "Chong-lou' agarwood originating from Aquilaria sinensis for the first time. Their new structures were elucidated on the basis of spectroscopic techniques (UV, IR, MS, 1D and 2D NMR), as well as by comparison with the literature data. Compounds 6 and 7 exhibited significant cytotoxicity against human cancer cell line K562 with IC50 values of 19.79 +/- 0.03 and 21.39 +/- 0.05 mu M, respectively.

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