A new phragmalin-type limonoid from the roots of Trichilia sinensis

文献类型: 外文期刊

第一作者: Yang, Jin-Ling

作者: Yang, Jin-Ling;Chen, Hui-Qin;Yang, Cheng-min;Wang, Hao;Cai, Cai-Hong;Yuan, Jing-Zhe;Mei, Wen-Li;Dai, Hao-Fu;Liu, Shou-Bai;Yang, Cheng-min

作者机构:

关键词: Trichilia sinensis; Meliaceae; Trichilinone A; AChE inhibitory activity

期刊名称:PHYTOCHEMISTRY LETTERS ( 影响因子:1.7; 五年影响因子:1.8 )

ISSN: 1874-3900

年卷期: 2023 年 53 卷

页码:

收录情况: SCI

摘要: A new 1,2-seco phragmalin-type limonoid, named trichilinone A, which contained a 1,30-oxo bridge in the tetranortriterpenoid core, was isolated from the roots of Trichilia sinensis (Meliaceae). The structure was eluci-dated based on the analysis of its HRESIMS and NMR spectroscopic data, and its absolute configuration was determined by single-crystal X-ray diffraction analysis. Compound 1 showed weak acetylcholinesterase inhibi-tory activity in vitro.

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