Histopathological and cytopathological findings in minipigs infected with Streptococcus suis serotype 2
文献类型: 外文期刊
第一作者: Xie, Chun
作者: Xie, Chun;Hou, Yi-Xuan;Zhao, Yu-Ting;Li, Cai-Ying;Su, Xue;Yue, Xiu-Wei;Yang, Wei-Jun;Yuan, Cong-Li;Cu, Li;Hua, Xiu-Guo;Yang, Zhi-Biao;Cai, Xue-Hui;Wang, Shu-Jie;Liu, Yong-Gang;Li, Cai-Ying;Li, Pei-Feng;Li, Yun-Zhang;Su, Xue;Yang, Wei-Jun
作者机构:
关键词: miniature pig;Streptococcus suis 2;experimental infection;histopathology;cytopathology.
期刊名称:BULLETIN OF THE VETERINARY INSTITUTE IN PULAWY ( 影响因子:0.643; 五年影响因子:0.547 )
ISSN:
年卷期:
页码:
收录情况: SCI
摘要: Five pathogen-free miniature pigs (minipigs) were infected with the virulent strain SH08 of Streptococcus suis 2 (SS2) by intramuscular injection. The pigs died consecutively within 72 h after the challenge. An additional five non-infected pigs were euthanised and used as controls. Microstructural observations showed that degeneration, bleeding, congestion, cellular necrosis, and an increase in inflammatory cells were present in all organs and tissues except the brain. Ultrastructural observations revealed mitochondrial vacuolation and malformed or missing cristae, indicating that infection of minipigs with strain SH08 of SS2 can lead to extensive lesions in major internal organs and tissues. The findings also demonstrated that the minipig is a useful model for the study of SS2 infection.
分类号: S85
- 相关文献
作者其他论文 更多>>
-
Minor envelope proteins from GP2a to GP4 contribute to the spread pattern and yield of type 2 PRRSV in MARC-145 cells
作者:Bai, Yuan-Zhe;Sun, Yue;Liu, Yong-Gang;Zhang, Hong-Liang;An, Tong-Qing;Wang, Qian;Tian, Zhi-Jun;Cai, Xue-Hui;Tang, Yan-Dong;Bai, Yuan-Zhe;Qiao, Xinyuan;Cai, Xue-Hui;Tang, Yan-Dong;Tang, Yan-Dong
关键词:spread pattern; PRRSV; cell-to-cell; cell-free; yield
-
MARCH1 and MARCH2 inhibit pseudorabies virus replication by trapping the viral cell-to-cell fusion complex in trans-Golgi network
作者:Huang, Rui;Rao, Cui-Hong;Bai, Yuan-Zhe;Chen, Meng;Peng, Jin-Mei;Xu, Shi-Jia;Sun, Yue;Fandan, Meng;Khan, Mirwaise;An, Tong-Qing;Tian, Zhi-Jun;Cai, Xue-Hui;Tang, Yan-Dong;Huang, Rui;Wang, Gang;Yu, Changqing;Chen, Meng;Cai, Xue-Hui;Tang, Yan-Dong;Chen, Meng;Tang, Yan-Dong;Lyu, Chuang
关键词:MARCH1; MARCH2; Pseudorabies virus; Herpesvirus; Cell-to-cell fusion; Glycoprotein B; Furin
-
Novel technologies are turning a dream into reality: conditionally replicating viruses as vaccines
作者:Tang, Yan-Dong;Cai, Xue-Hui;Yu, Changqing;Tang, Yan-Dong;Cai, Xue-Hui;Tang, Yan-Dong
关键词:
-
MARCH8 inhibits pseudorabies virus replication by trapping the viral cell-to-cell fusion complex in the trans-Golgi network
作者:Rao, Cui-Hong;Huang, Rui;Bai, Yuan-Zhe;Chen, Meng;Peng, Jin-Mei;Xu, Shi-Jia;Sun, Ming-Xia;Wang, Shu-Jie;Yang, Yong-Bo;An, Tong-Qing;Tian, Zhi-Jun;Lyu, Chuang;Cai, Xue-Hui;Meng, Fandan;Tang, Yan-Dong;Yu, Changqing;Sun, Ming-Xia;Cai, Xue-Hui;Tang, Yan-Dong;Sun, Ming-Xia;Lyu, Chuang;Tang, Yan-Dong;Zheng, Chunfu
关键词:MARCH8; Cell-to-cell fusion; TGN
-
The N-glycosylation at positions 652 and 661 of viral spike protein negatively modulates porcine deltacoronavirus entry
作者:Wang, Hai-Ming;Qiao, Yang-Yang;Cai, Bing-Yan;Lu, Hui;Liu, Yong-Gang;Yang, Yue-Lin;Tang, Yan-Dong;Tang, Yan-Dong
关键词:PDCoV; N-glycosylation; entry; pseudotyped virus; spike protein
-
Lipid A-modified Escherichia coli can produce porcine parvovirus virus-like particles with high immunogenicity and minimal endotoxin activity
作者:Shen, Xuegang;Yang, Yong-Bo;Gao, Yanfei;Wang, Shujie;Wang, Haiwei;Sun, Mingxia;Meng, Fandan;Tang, Yan-Dong;Tu, Yabin;An, Tong-Qing;Cai, Xue-Hui;Kong, Qingke;An, Tong-Qing;Yang, Yong-Bo;Cai, Xue-Hui
关键词:Porcine parvovirus; Virus-like particle; Minimal endotoxin activity; Escherichia coli; Lipid A
-
A novel viral vaccine platform based on engineered transfer RNA
作者:Wang, Tong-Yun;Meng, Fan-Dan;Zhang, Hong-Liang;Tian, Zhi-Jun;Cai, Xue-Hui;Tang, Yan-Dong;Wang, Tong-Yun;Meng, Fan-Dan;Cai, Xue-Hui;Tang, Yan-Dong;Sang, Guo-Ju;Zheng, Hao;Cai, Xue-Hui;Tang, Yan-Dong;Tang, Yan-Dong;Zheng, Hao;Cai, Xue-Hui;Cai, Xue-Hui
关键词:Engineered transfer RNA; PTC virus; vaccine; switch; Pseudorabies virus; novel vaccine