Two Androstane Derivatives from the Cultures of Fungus Marasmiellus ramealis (Bull.) Singer
文献类型: 外文期刊
第一作者: Yang, Ning-Ning
作者: Yang, Ning-Ning;Ma, Qing-Yun;Huang, Sheng-Zhuo;Dai, Hao-Fu;Guo, Zhi-Kai;Zhao, You-Xing;Yang, Ning-Ning;Yu, Zhi-Fang
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关键词: Marasmiellus ramealis (Bull.) Singer;Fermentation;Androstane derivative;AChE inhibitory activity
期刊名称:BULLETIN OF THE KOREAN CHEMICAL SOCIETY ( 影响因子:0.969; 五年影响因子:0.691 )
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收录情况: SCI
摘要: A new androstane derivative, 4β-memyl-15-oxa-14β-androstane-7-ene-4α-carboxylic acid (1) and a known one 4βmethyl-15-oxa-14β-androstane-7-ene-4α-hydroxyl (2) were isolated from the EtOAc extract of the cultures of the fungus Marasmiellus ramealis (Bull.) Singer. Their structures were elucidated on the basis of 1D and 2D NMR as well as MS spectroscopic data analysis. The inhibitory activity of two isolates against acetylcholinesterase (AChE) revealed that compound 1 exhibited definitely inhibitory activity.
分类号: O6
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