Differentiation of chicken umbilical cord mesenchymal stem cells into beta-like pancreatic islet cells
文献类型: 外文期刊
第一作者: Bai, Chunyu
作者: Bai, Chunyu;Gao, Yuhua;Li, Qian;Feng, Yuan;Yu, Yanze;Meng, Gentong;Zhang, Minghai;Bai, Chunyu;Gao, Yuhua;Li, Qian;Guan, Weijun
作者机构:
关键词: chicken;islet cells;mesenchymal stem cells;umbilical cord
期刊名称:ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY ( 影响因子:5.678; 五年影响因子:5.246 )
ISSN:
年卷期:
页码:
收录情况: SCI
摘要: In this study, we explored the possibility of using in vitro differentiation to create functional beta-like islet cells from chicken umbilical cord mesenchymal stem cells (UCMSCs). Passaged UCMSCs were induced to differentiate into pancreatic beta-like islet cells. Differentiated cells were observed through dithizone staining, and Pdx1 and insulin expressed in differentiated cells were detected with immunofluorescence. Insulin and C-peptide production from differentiated cells were analyzed using ELISA and western blotting. Differentiated cells were found to not only express Pdx1, insulin, and C-peptide, but also to display a glucose-responsive secretion of these hormones.
分类号: R31
- 相关文献
作者其他论文 更多>>
-
Effects of fermentation duration on the flavour quality of large leaf black tea based on metabolomics
作者:Dong, Haiyu;Li, Yonghui;Wang, Baijuan;Liu, Xiaohui;Lai, Xingfei;Hao, Mengjiao;Sun, Lingli;Li, Qiuhua;Chen, Ruohong;Sun, Shili;Zhang, Zhenbiao;Li, Qian
关键词:Black tea; Fermentation; Taste quality; Composition; Metabolomics
-
Sulfur-containing iron carbon nanocomposites activate persulfate for combined chemical oxidation and microbial remediation of petroleum-polluted soil
作者:Ma, Mengyu;An, Ning;Cui, Zhaojie;Li, Qian;Wang, Yanqin;Zhao, Chao;Zhou, Weizhi;Gu, Meixia
关键词:Petroleum -polluted soil; Persulfate activation; Sulfur -containing iron carbon nanocomposites; Indigenous microbial remediation
-
Flowering apricot trees increase the abundance and modulate the distribution of wild bees within Korla fragrant pear ( Pyrus sinkiangensis) ) orchards, but apricot trees in the surrounding landscape do not increase wild bee abundance
作者:Li, Qian;Liu, Bing;Lu, Yanhui;Li, Qian;van der Werf, Wopke;Li, Qian;Bianchi, Felix J. J. A.
关键词:Pollinating insect; Fruit production; Diversification; Early flowering crops
-
Response of Soil Nitrogen Components and nirK- and nirS-Type Denitrifying Bacterial Community Structures to Drip Irrigation Systems in the Semi-Arid Area of Northeast China
作者:Qiang, Ruowen;Li, Yingjie;Sun, Huixian;Liang, Wenyu;Li, Cuilan;Zhang, Jinjing;Liu, Hang;Wang, Meng;Li, Qian
关键词:drip irrigation; nirS gene; nirK gene; nitrate reductase; N components
-
Stability and integrity of self-assembled bovine parvovirus virus-like particles (BPV-VLPs) of VP2 and combination of VP1VP2 assisted by baculovirus-insect cell expression: a potential logistical platform for vaccine deployment
作者:Wubshet, Ashenafi Kiros;Li, Guo-xiu;Li, Qian;Dai, Jun-Fei;Ding, Yao-Zhong;Zhou, Luoyi;Qu, Min;Wang, Yang;Ma, Zhongyuan;Kebede, Asmelash Tassew;Sun, Yuefeng;Yin, Xiangping;Liu, Yongsheng;Jie, Zhang;Liu, Yongsheng;Jie, Zhang;Wubshet, Ashenafi Kiros;Abera, Birhanu Hadush;Kebede, Asmelash Tassew;Werid, Gebremeskel Mamu
关键词:Bovine parvovirus; Physicochemical properties; Secondary structure; Virus-like particle; VP2; VP1VP2
-
Preparation and chemical properties of microencapsulation developed with mulberry anthocyanins and silk fibroin
作者:Shi, Yingchun;Chen, Xiangyue;Zou, Yuxiao;Xing, Dongxu;Li, Qian;Gao, Qunyu;Chen, Ruohong;He, Xuemei;Li, Qian
关键词:Mulberry anthocyanins; Microcapsules; Silk fibroin; Agricultural products processing
-
The APETALA2-MYBL2 module represses proanthocyanidin biosynthesis by affecting formation of the MBW complex in seeds of Arabidopsis thaliana
作者:Jiang, Wenbo;Li, Qian;Zhang, Jin;Pang, Yongzhen;Yin, Qinggang;Liu, Jinyue;Su, Xiaojia;Han, Xiaoyan
关键词: