Photoactivation and inactivation of Arabidopsis cryptochrome 2

文献类型: 外文期刊

第一作者: Wang, Qin

作者: Wang, Qin;Zuo, Zecheng;Wang, Xu;Gu, Lianfeng;Yang, Zhaohe;Yang, Liang;Liu, Qing;Oka, Yoshito;Lin, Chentao;Wang, Qin;Wang, Xu;Liu, Qing;Lin, Chentao;Zuo, Zecheng;Yang, Liang;Liu, Qing;Liu, Wei;Yoshizumi, Takeshi;Matsui, Minami;Oka, Yoshito;Han, Yun-Jeong;Kim, Jeong-Il;Han, Yun-Jeong;Kim, Jeong-Il;Liu, Bin;Wohlschlegel, James A.

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期刊名称:SCIENCE ( 影响因子:47.728; 五年影响因子:51.433 )

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收录情况: SCI

摘要: Cryptochromes are blue-light receptors that regulate development and the circadian clock in plants and animals. We found that Arabidopsis cryptochrome 2 (CRY2) undergoes blue light-dependent homodimerization to become physiologically active. We identified BIC1 (blue-light inhibitor of cryptochromes 1) as an inhibitor of plant cryptochromes that binds to CRY2 to suppress the blue light-dependent dimerization, photobody formation, phosphorylation, degradation, and physiological activities of CRY2. We hypothesize that regulated dimerization governs homeostasis of the active cryptochromes in plants and other evolutionary lineages.

分类号: N

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