Experimental infection of duck origin virulent Newcastle disease virus strain in ducks

文献类型： 外文期刊

第一作者： Dai, Yabin

作者： Dai, Yabin;Cheng, Xu;Liu, Mei;Shen, Xinyue;Li, Jianmei;Zou, Jianmin;Dai, Yabin;Cheng, Xu;Liu, Mei;Shen, Xinyue;Li, Jianmei;Zou, Jianmin;Yu, Shengqing;Ding, Chan

作者机构：

关键词： Newcastle disease virus;Duck;Breed;Age;Susceptibility;Pathogenesis;Virus shedding

期刊名称：BMC VETERINARY RESEARCH （ 影响因子：2.741； 五年影响因子：2.955 ）

ISSN： 1746-6148

年卷期： 2014 年 10 卷

页码：

收录情况： SCI

摘要： Background: Newcastle disease (ND) caused by virulent Newcastle disease virus (NDV) is an acute, highly contagious and fatal viral disease affecting most species of birds. Ducks are generally considered to be natural reservoirs or carriers of NDV while being resistant to NDV strains, even those most virulent for chickens; however, natural ND cases in ducks have been gradually increasing in recent years. In the present study, ducks of different breeds and ages were experimentally infected with duck origin virulent NDV strain duck/Jiangsu/JSD0812/2008 (JSD0812) by various routes to investigate the pathogenicity of NDV in ducks. Results: Six breeds (mallard, Gaoyou, Shaoxing, Jinding, Shanma, and Pekin ducks) were infected intramuscularly (IM) with JSD0812 strain at the dose of 5 x 10(8) ELD50. Susceptibility to NDV infection among breeds varied, per morbidity and mortality. Mallard ducks were the most susceptible, and Pekin ducks the most resistant. Fifteen-, 30-, 45-, 60-, and 110-day-old Gaoyou ducks were infected with JSD0812 strain at the dose of 5 x 10(8) ELD50 either IM or intranasally (IN) and intraocularly (IO), and their disease development, viral shedding, and virus tissue distribution were determined. The susceptibility of ducks to NDV infection decreased with age. Most deaths occurred in 15- and 30-day-old ducklings infected IM. Ducks infected IN and IO sometimes exhibited clinical signs, but seldom died. Clinical signs were primarily neurologic. Infected ducks could excrete infectious virus from the pharynx and/or cloaca for a short period, which varied with bird age or inoculation route; the longest period was about 7 days. The rate of virus isolation in tissues from infected ducks was generally low, even in those from dead birds, and it appeared to be unrelated to bird age and infection route. Conclusions: The results confirmed that some of the naturally occurring NDV virulent strains can cause the disease in ducks, and that ducks play an important role in the epidemiology of ND. The prevention of NDV spread in ducks should receive more attention and research in terms of preventing the occurrence and prevalence of ND.

分类号：

  • 相关文献

[1]Infectivity and Pathogenicity of Newcastle Disease Virus Strains of Different Avian Origin and Different Virulence for Mallard Ducklings. Dai, Yabin,Liu, Mei,Cheng, Xu,Shen, Xinyue,Wei, Yuyong,Zhou, Sheng,Yu, Shengqing,Ding, Chan. 2013

[2]Development Rule of Intramuscular Fat Content in Chicken. Chang Guo-Bin,Lei Li-Li,Chen Rong,Luan De-Qin,Chen Guo-Hong,Zhang Xue-Yu,Wang Ke-Hua,Wang Ke-Hua. 2010

[3]Comparative proteome analysis of tracheal tissues in response to infectious bronchitis coronavirus, Newcastle disease virus, and avian influenza virus H9 subtype virus infection. Sun, Junfeng,Han, Zongxi,Shao, Yuhao,Cao, Zhongzan,Kong, Xiangang,Liu, Shengwang.

[4]Host Innate Immune Responses of Ducks Infected with Newcastle Disease Viruses of Different Pathogenicities. Kang, Yinfeng,Li, Yanling,Yuan, Runyu,Feng, Minsha,Xiang, Bin,Sun, Minhua,Li, Yaling,Xie, Peng,Tan, Yangtong,Ren, Tao,Kang, Yinfeng,Li, Yanling,Yuan, Runyu,Feng, Minsha,Xiang, Bin,Sun, Minhua,Li, Yaling,Xie, Peng,Tan, Yangtong,Ren, Tao,Kang, Yinfeng,Li, Yanling,Feng, Minsha,Xiang, Bin,Ren, Tao,Yuan, Runyu,Sun, Minhua. 2015

[5]Two myeloid differentiation factor 88 (MyD88) isoforms identified in ducks. Cheng, Yuqiang,Wang, Hengan,Yan, Yaxian,Sun, Jianhe,Ding, Chan.

[6]Cloning, expression and functional analysis of the duck Toll-like receptor 5 (TLR5) gene. Cheng, Yuqiang,Wang, Hengan,Shi, Shuduan,Yan, Yaxian,Sun, Jianhe,Sun, Yingjie,Ding, Chan,Li, Jing.

[7]Effect of parasitism on flight behavior of the soybean aphid, Aphis glycines. Wu, Kongming,Wyckhuys, Kris A. G.,Heimpel, George E..

[8]Generation and Evaluation of a Newcastle Disease Virus-Based H9 Avian Influenza Live Vaccine. Bu, Zhigao.

[9]Protective Efficacy of H7 Subtype Avian Influenza DNA Vaccine. Chen, Hualan.

[10]SNP discovery and genotyping using restriction-site-associated DNA sequencing in chickens. Zhai, Zhengxiao,Zhao, Wenjing,He, Chuan,Liu, Shuyun,Meng, He,He, Chuan,Yang, Kaixuan,Tang, Linlin,Huang, Qizhong,Zhang, Yan.

[11]Effectiveness of a 95 SNP panel for the screening of breed label fraud in the Chinese meat market. Rogberg-Munoz, A.,Ripoli, M. V.,Carino, M. H.,Liron, J. P.,Peral-Garcia, P.,Giovambattista, G.,Rogberg-Munoz, A.,Wei, S.,Guo, B. L.,Wei, Y. M.,Prando, A. J.,Vaca, R. J. A..

[12]A Novel 15 bp Deletion Mutation at KAP16.5 Locus in Cashmere Goat of China. Jun, Liu Wu,Yi, Fang,Shao Yong-gang,Xin, Fang Guang,Quan, Zhang Fu,Hong, Chen,Hong, Chen,Chuan, Tian Ke.

[13]A genome-wide scan for signatures of selection in Chinese indigenous and commercial pig breeds. Yang, Songbai,Li, Kui,Tang, Zhonglin,Yang, Songbai,Li, Xiuling,Fan, Bin,Yang, Songbai,Li, Xiuling,Fan, Bin. 2014

[14]Foreign meat identification by DNA breed assignment for the Chinese market. Rogberg-Munoz, A.,Ripoli, M. V.,Carino, M. H.,Castillo, N.,Villegas Castagnaso, E. E.,Liron, J. P.,Morales Durand, H. F.,Peral-Garcia, P.,Giovambattista, G.,Wei, S.,Guo, B. L.,Wei, Y. M.,Melucci, L.,Villarreal, E..

[15]Effects of breeds on the formation of heterocyclic aromatic amines in smoked lamb. Hou, Chengli,Wang, Zhenyu,Wu, Liguo,Chai, Jiali,Song, Xuan,Wang, Wenting,Zhang, Dequan.

[16]The fecal microbiota composition of boar Duroc, Yorkshire, Landrace and Hampshire pigs. Xiao, Yingping,Li, Kaifeng,Gui, Guohong,Yang, Hua,Xiao, Yingping,Li, Kaifeng,Gui, Guohong,Yang, Hua,Li, Kaifeng,Xiang, Yun,Zhou, Weidong.

[17]First report of the molecular detection of Ancylostoma caninum in Lahore, Pakistan: the threat from pets. Rehman, A.,Shehzad, W.,Islam, S.,Bajwa, A. A.,Akhtar, R.,Rashid, I.,Akbar, H.,Riaz, F.,Waqas, M.. 2017

[18]Effects of constant temperature, exposure period, and age on diapause induction in Trichogramma dendrolimi. Ma, CS,Chen, YW. 2006

[19]Estimation of the Age and Amount of Brown Rice Plant Hoppers Based on Bionic Electronic Nose Use. Xu, Sai,Zhou, Zhiyan,Lu, Huazhong,Luo, Xiwen,Lan, Yubin,Xu, Sai,Zhou, Zhiyan,Lu, Huazhong,Luo, Xiwen,Lan, Yubin,Lan, Yubin,Zhang, Yang,Li, Yanfang,Zhang, Yang,Li, Yanfang. 2014

[20]Hyperoside Downregulates the Receptor for Advanced Glycation End Products (RAGE) and Promotes Proliferation in ECV304 Cells via the c-Jun N-Terminal Kinases (JNK) Pathway Following Stimulation by Advanced Glycation End-Products In Vitro. Zhang, Zhengyu,Shen, Weizhi,Liao, Sentai,Zou, Yuxiao,Zhang, Zhengyu,Sethiel, Mosha Silas. 2013

作者其他论文 更多>>

微信小程序