Hydrogel-based 3D printing technology: From interfacial engineering to precision medicine

文献类型： 外文期刊

第一作者： Wu, Haojie

作者： Wu, Haojie;Yue, Dongmei;Li, Peipei;Wu, Haojie;Diao, Jibo;Li, Xinrong;He, Gaohong;Jiang, Xiaobin

作者机构：

关键词： Hydrogel; 3D printing; Disease detection; Drug delivery; Regeneration

期刊名称：ADVANCES IN COLLOID AND INTERFACE SCIENCE （ 影响因子：19.3； 五年影响因子：19.5 ）

ISSN： 0001-8686

年卷期： 2025 年 341 卷

页码：

收录情况： SCI

摘要： Advances in 3D printing technology and the development of hydrogel-based inks have significantly enhanced the potential of precision medicine, promoting progress in medical diagnosis and treatment. The development of 3D printing enables the fabrication of complex gradient structures that emulate natural tissue environments, while advancements in interface engineering facilitate the precise control of interface properties, thereby enhancing the performance of hydrogels in biomedical applications. This review focuses on the latest advancements in three critical 3D printing application areas: efficient real-time detection, drug delivery systems, and regenerative medicine. The application of 3D printing technology enhances nucleic acid-based molecular diagnostic platforms and wearable biosensors for real-time monitoring of physiological parameters, thereby providing robust support for early disease diagnosis. Additionally, it facilitates the development of targeted and controlled drug delivery systems, which offer promising methods for efficient drug utilization, and enables the construction of complex tissue and organ structures with bioactivity and functionality, providing new solutions for regenerative medicine. Collectively, these advancements propel the ongoing progress and development of precision medicine. Furthermore, the challenges associated with 3D printing technology in these three major applications are discussed along with an outlook on prospects.

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