Influences of Selenium on the Duckling Hepatic Mitochondrial Membrane Permeability Changes Induced by Aflatoxin B-1

文献类型： 外文期刊

第一作者： Shi, D. -Y.

作者： Shi, D. -Y.;Guo, S. -N.;Tang, Z. -X.;Liao, S. -Q.

作者机构：

关键词： Aflatoxin B-1;Hepatic mitochondrial;Membrane permeability;Duckling;Sodium selenite

期刊名称：2011 INTERNATIONAL CONFERENCE ON FUZZY SYSTEMS AND NEURAL COMPUTING (FSNC 2011), VOL VII

ISSN：

年卷期： 2011 年

页码：

收录情况： SCI

摘要： In order to observe the influences of aflatoxin B1 (AFB1) on hepatic mitochondrial membrane permeability in ducklings and study the antagonistic effect of sodium selenite (Na2SeO3) on AFBI. Seven day-old ducklings were used as experimental animals. All animals were divided into three groups (30 animals each). The ducklings of group I was fed on the same volume of DMSO only with the other group as control. Group II, III were administered intragastrically AFB1 at a dose 0.1mg/kg body weight respectively, and group III was fed on sodium selenite at a dose 1mg/kg. All treatments were given once daily during 7-28 day-old. The duckling hepatic mitochondrial membrane permeability was detected on 7th, 14th, 21th day after treatment. The results showed that the ducklings hepatic mitochondrial membrane permeability in AFB(1) treated ducklings (Group II, III) was higher than group I (P<0.05), and the hepatic mitochondrial membrane permeability of group II was higher than sodium selenite treated group (group III) (P<0.05). These results revealed that sodium selenite could ameliorate the duckling hepatic mitochondrial membrane permeability changes induced by aflatoxin B-1.

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