Effect of transgenic expression of porcine interleukin-6 gene and CpG sequences on immune responses of newborn piglets inoculated with Pseudorabies attenuated vaccine

文献类型: 外文期刊

第一作者: Zhang, LH

作者: Zhang, LH;Tian, XS;Guo, Y;Zhou, FZ;Meng, MJ

作者机构:

关键词: newborn piglets;pseudorabies attenuated vaccine;CpG motifs;immune response;interleukin-6

期刊名称:RESEARCH IN VETERINARY SCIENCE ( 影响因子:2.534; 五年影响因子:2.382 )

ISSN: 0034-5288

年卷期: 2006 年 80 卷 3 期

页码:

收录情况: SCI

摘要: Porcine interleukin-6 gene and CpG sequences were used as immunoadjuvants to enhance the immune responses of newborn piglets to Pseudorabies attenuated vaccine (PAV). The titer of specific antibodies to PAV, the proliferation of lymphocytes and induced IL-2 activities were all examined to identify the immune response of the piglets. The results showed that the immune responses with CpG ODN and porcine interleukin-6 gene were significantly stronger than routine immunities. The data suggests that porcine IL-6 and CpG motifs could be employed as effective immunoadjuvants to raise the humoral and cellular responses of newborn piglets to Pseudorabies attenuated vaccine. (c) 2005 Elsevier Ltd. All rights reserved.

分类号:

  • 相关文献

[1]Effects of CpG ODN on CD4(+) and CD8(+) T subpopulations in the immune response to porcine reproductive and respiratory syndrome killed virus vaccine. Zhang, LH,Tian, XS,Guo, Y,Zhou, FZ. 2006

[2]Morphological and Immunohistochemical Identification of Villous M Cells in the Small Intestine of Newborn Piglets. Li Renfeng,Zhou Enmin,Li Renfeng,Tian Xiangqin,Qiao Songlin,Yang Yanyan,Zhang Gaiping. 2015

[3]Immunogenicity of porcine circovirus type 2 nucleic acid vaccine containing CpG motif for mice. Li, Jun,Yu, Jiang,Xu, Shaojian,Shi, Jianli,Xu, Shengnan,Wu, Xiaoyan,Peng, Zhe,Zhang, Lingling,Zheng, Shuxuan,Yuan, Xiaoyuan,Cong, Xiaoyan,Sun, Wenbo,Cheng, Kaihui,Du, Yijun,Wu, Jiaqiang,Wang, Jinbao,Fu, Fang. 2016

[4]Dietary black-grained wheat intake improves glycemic control and inflammatory profile in patients with type 2 diabetes: a randomized controlled trial. Liu, Yanping,Qiu, Ju,Yue, Yanfen,Li, Kang,Ren, Guixing. 2018

[5]Callicarpa japonica Thunb. reduces inflammatory responses: A mouse model of lipopolysaccharide-induced acute lung injury. Shin, Na-Rae,Shin, In-Sik,Song, Hyuk-Hwan,Hong, Ju-Mi,Kwon, Ok-Kyoung,Jeon, Chan-Mi,Kim, Jung-Hee,Oh, Sei-Ryang,Ahn, Kyung-Seop,Shin, Na-Rae,Hahn, Kyu-Woung,Shin, In-Sik,Lee, Sang-Woo,Lee, Joong-Ku,Jin, Hang,Li, Wan Yi. 2015

[6]Identification of Splice Variants, Targeted MicroRNAs and Functional Single Nucleotide Polymorphisms of the BOLA-DQA2 Gene in Dairy Cattle. Hou, Qinlei,Huang, Jinming,Ju, Zhihua,Li, Qiuling,Li, Liming,Wang, Changfa,Sun, Tao,Wang, Lingling,Hou, Minghai,Zhong, Jifeng,Hang, Suqin.

[7]Marburg virus-like particles produced in insect cells induce neutralizing antibodies in rhesus macaques. Gai Weiwei,Gai Weiwei,Zhao Yongkun,Wang Qi,Wang Hualei,Xie Ying,Wang Haijun,Cao Zengguo,Feng Na,Chi Hang,Wang Tiecheng,Gao Yuwei,Yang Songtao,Xia Xianzhu,Zheng Xuexing,Wang Chong,Wang Qi,Wong Gary,Shan Junjie.

[8]Identification of Th1 epitopes within molecules from the lung-stage schistosomulum of Schistosoma japonicum by combining prediction analysis of the transcriptome with experimental validation. Zhang, Yan Li,Jia, Kan,Zhao, Ben Peng,Li, Ying,Yuan, Chun Xiu,Yang, Jian Mei,Lin, Jiao Jiao,Feng, Xin Gang,Jia, Kan,Zhao, Ben Peng,Li, Ying.

[9]A mutation in the NLRC5 promoter limits NF-kappa B signaling after Salmonella Enteritidis infection in the spleen of young chickens. Chang, Guobin,Ma, Teng,Xu, Lu,Wang, Hongzhi,Li, Zhiteng,Guo, Xiaomin,Xu, Qi,Chen, Guohong,Liu, Xiangping.

[10]Effect of zinc source on performance, zinc status, immune response, and rumen fermentation of lactating cows. Wang, Run L.,Liang, Jian G.,Lu, Lin,Zhang, Li Y.,Li, Su F.,Luo, Xu G.,Wang, Run L.,Li, Su F..

[11]Porcine GPX1 enhances GP5-based DNA vaccination against porcine reproductive and respiratory syndrome virus. Du, Luping,Pang, Fengjiao,Xu, Xiangwei,Huang, Kehe,Du, Luping,Li, Bin,Pang, Fengjiao,Yu, Zhengyu,Xu, Xiangwei,Fan, Baochao,Tan, Yeping,He, Kongwang,Du, Luping,Li, Bin,Yu, Zhengyu,Fan, Baochao,Tan, Yeping,He, Kongwang.

[12]Co-administration of porcine-specific CpG oligodeoxynucleotide enhances the immune responses to pseudorabies attenuated virus vaccine in newborn piglets in vivo. Zhang, LH,Guo, Y,Tian, XS,Zhou, FZ.

[13]Effect of long-term administration of dietary beta-1,3-glucan on growth, physiological, and immune responses in Litopenaeus vannamei (Boone, 1931). Zhao, Hong-Xia,Wang, An-Li,Ye, Chao-Xia,Zhao, Hong-Xia,Cao, Jun-Ming,Huang, Yan-Hua,Lan, Han-Bing,Zhou, Ting-Ting,Li, Guo-Li,Du, Zhen-Yu.

[14]Effect of dietary beta-1,3-glucan on the immune response of Litopenaeus vannamei exposed to nitrite-N. Zhao, H-X,Cao, J-M,Huang, Y-H,Li, G-L,Lan, H-B,Zhao, H-X,Wang, A-L,Tian, J-X,Du, Z-Y.

[15]Immune responses in piglets infected with highly pathogenic porcine reproductive and respiratory syndrome virus. Wang, Gang,Song, Tengfei,Liu, Yonggang,Shi, Wenda,Wang, Shujie,Rong, Fulong,Dong, Jianguo,Liu, He,Cai, Xuehui,Wang, Gang,Song, Tengfei,Yu, Ying,Zhou, En-Min,Zhou, En-Min.

[16]Effects of dietary glycyl-glutamine on growth performance, small intestinal integrity, and immune responses of weaning piglets challenged with lipopolysaccharide. Jiang, Z. Y.,Lin, Y. C.,Ma, X. Y.,Zheng, C. T.,Zhou, G. L.,Chen, F.,Zou, S. T.,Sun, L. H..

[17]Vaccination with Different M2e Epitope Densities Confers Partial Protection against H5N1 Influenza A Virus Challenge in Chickens. Liu, Ming.

[18]Up-regulation of the MyD88-dependent pathway of TLR signaling in spleen and caecum of young chickens infected with Salmonella serovar Pullorum. Li, Peng,Wen, Jie,Zheng, Maiqing,Chen, Jilan,Zhao, Jingpeng,Jiang, Ruirui,Liu, Ranran,Zhao, Guiping,Li, Peng,Xia, Pingan.

[19]Newcastle disease virus-like particles induce dendritic cell maturation and enhance viral-specific immune response. Qian, Jing,Ding, Jiaxin,Yin, Renfu,Xue, Cong,Xu, Xiaohong,Cong, Yanlong,Ding, Zhuang,Qian, Jing,Ding, Jiaxin,Yin, Renfu,Xue, Cong,Xu, Xiaohong,Cong, Yanlong,Ding, Zhuang,Sun, Yixue,Wang, Jianzhong,Ding, Chan,Yu, Shengqing,Liu, Xiufan,Hu, Shunlin.

[20]Porcine epidemic diarrhea virus virus-like particles produced in insect cells induce specific immune responses in mice. Wang, Cuiling,Wang, Cuiling,Yan, Feihu,Zheng, Xuexing,Wang, Hualei,Jin, Hongli,Wang, Chong,Zhao, Yongkun,Feng, Na,Wang, Tiecheng,Gao, Yuwei,Yang, Songtao,Xia, Xianzhu,Zheng, Xuexing,Jin, Hongli,Wang, Chong,Zheng, Xuexing,Wang, Hualei,Zhao, Yongkun,Feng, Na,Wang, Tiecheng,Gao, Yuwei,Yang, Songtao,Xia, Xianzhu.

作者其他论文 更多>>