文献类型： 外文期刊
作者： Jiang, Yao 1 ; He, Yingting 3 ; Pan, Xiangchun 3 ; Wang, Penghao 1 ; Yuan, Xiaolong 3 ; Ma, Bin 1 ;
作者机构： 1.Murdoch Univ, Sch Med Mol & Forens Sci, Murdoch, WA 6149, Australia
2.Chinese Acad Agr Sci, Shenzhen Branch, Guangdong Lab Lingnan Modern Agr, Genome Anal Lab,Minist Agr,Agr Genom Inst Shenzhen, Shenzhen 518120, Peoples R China
3.South China Agr Univ, Guangdong Lab Lingnan Modern Agr, Natl Engn Res Ctr Breeding Swine Ind, Guangdong Prov Key Lab Agroanim Genom & Mol Breedi, Guangzhou 510642, Peoples R China
关键词： folliculogenesis; oogenesis; oocyte; in vivo maturation; in vitro maturation; single-cell mRNA sequencing
期刊名称：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES （ 影响因子：5.6； 五年影响因子：6.2 ）
ISSN： 1661-6596
年卷期： 2023 年 24 卷 10 期
页码：
收录情况： SCI
摘要： The quality and maturation of an oocyte not only play decisive roles in fertilization and embryo success, but also have long-term impacts on the later growth and development of the fetus. Female fertility declines with age, reflecting a decline in oocyte quantity. However, the meiosis of oocytes involves a complex and orderly regulatory process whose mechanisms have not yet been fully elucidated. This review therefore mainly focuses on the regulation mechanism of oocyte maturation, including folliculogenesis, oogenesis, and the interactions between granulosa cells and oocytes, plus in vitro technology and nuclear/cytoplasm maturation in oocytes. Additionally, we have reviewed advances made in the single-cell mRNA sequencing technology related to oocyte maturation in order to improve our understanding of the mechanism of oocyte maturation and to provide a theoretical basis for subsequent research into oocyte maturation.
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