Mechanism of Rotenone Toxicity against Plutella xylostella: New Perspective from a Spatial Metabolomics and Lipidomics Study
文献类型： 外文期刊
作者： Li, Ping 1 ; Tian, Yongqing 1 ; Du, Mingyi 1 ; Xie, Qingrong 1 ; Chen, Yingying 1 ; Ma, Lianlian 1 ; Huang, Yudi 1 ; Yin, Zhibin 4 ; Xu, Hanhong 1 ; Wu, Xinzhou 1 ;
作者机构： 1.South China Agr Univ, State Key Lab Conservat & Utilizat Subtrop Agrobio, Guangzhou 510642, Peoples R China
2.South China Agr Univ, Minist Educ, Key Lab Nat Pesticide & Chem Biol, Guangzhou 510642, Peoples R China
3.South China Agr Univ, Coll Plant Protect, Key Lab Biopesticide Creat & Applicat Guangdong Pr, Guangzhou 510642, Peoples R China
4.Guangdong Acad Agr Sci, Agrobiol Gene Res Ctr, Guangzhou 510640, Peoples R China
关键词： rotenone; Plutella xylostella; metabolomics; lipidomics; mass spectrometry imaging
期刊名称：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY （ 影响因子：5.895； 五年影响因子：6.048 ）
ISSN： 0021-8561
年卷期：
页码：
收录情况： SCI
摘要： The botanical pesticide rotenone can effectively control target pest Plutella xylostella, yet insights into in situ metabolic regulation of P. xylostella toward rotenone remain limited. Herein, we demonstrated metabolic expression levels and spatial distribution of rotenone-treated P. xylostella using spatial metabolomics and lipidomics. Specifically, rotenone significantly affected purine and amino acid metabolisms, indicating that adenosine monophosphate and inosine were distributed in the whole body of P. xylostella with elevated levels, while guanosine 5 '-monophosphate and tryptophan were significantly downregulated. Spatial lipidomics results indicated that rotenone may significantly destroy glycerophospholipids in cell membranes of P. xylostella, inhibit fatty acid biosynthesis, and consume diacylglycerol to enhance fat oxidation. These findings revealed that high toxicity of rotenone toward P. xylostella may be ascribed to negative effects on energy production and amino acid synthesis and damage to cell membranes, providing guidelines for the toxicity mechanism of rotenone on target pests and rational development of botanical pesticide candidates.
- 相关文献
作者其他论文 更多>>
-
Advances in mass spectrometry imaging for plant metabolomics-Expanding the analytical toolbox
作者：Yin, Zhibin;Huang, Wenjie;Yan, Shijuan;Yin, Zhibin;Li, Kun;Fernie, Alisdair R.
关键词：mass spectrometry imaging; plant metabolomics; spatial multi-omics; MALDI; DESI; spatial resolution; ionization efficiency
-
Comparative physiological and transcriptome analysis provide insights into the inhibitory effect of osthole on Penicillium choerospondiatis
作者：Lai, Duo;Wang, Delin;Shao, Xuehua;Qin, Jian;Zhuang, Qingli;Xiao, Weiqiang;Xu, Hanhong;Xiao, Weiqiang
关键词：Penicillium choerospondiatis; Osthole; Antifungal activity; Transcriptome analysis; Autophagy
-
Bruceine D inhibits the growth of Spodoptera litura by inducing cell apoptosis in the midgut via an oxidative burst
作者：Zeng, Jiwu;Mao, Genlin;Xu, Yuhui;Zeng, Jiwu;Lu, Wei;Xu, Yuhui;Liu, Huan;Xu, Hanhong;Xu, Hanhong
关键词：Bruceine D; Spodoptera litura; growth and development; midgut; ROS; apoptosis
-
Novel Phosphate Transporter-B PvPTB1;1/1;2 Contribute to Efficient Phosphate Uptake and Arsenic Accumulation in As-Hyperaccumulator Pteris vittata
作者：Sun, Dan;Zhang, Xiang;Zeng, Zihan;Feng, Huayuan;Tang, Yetao;Qiu, Rongliang;Cao, Yue;Feng, Huayuan;Tang, Yetao;Cao, Yue;Yin, Zhibin;Guo, Nan;Tang, Yetao;Qiu, Rongliang;Cao, Yue;Qiu, Rongliang;Qiu, Rongliang;Ma, Lena Q.
关键词：phytoremediation; low-affinity P transporters PvPTB1;1/1;2; dual P uptakesystem; high-affinity P transporter Pht1; phytatesecretion and hydrolysis; P/As transporters
-
Influence of Two Hexose Transporters on Substrate Affinity and Pathogenicity in Magnaporthe oryzae
作者：Huang, Tinghong;Guo, Dekang;Luo, Xiao;Chen, Ronghua;Xu, Hanhong;Lin, Fei;Wang, Wenjuan;Chen, Shen
关键词：hexose transporters; pathogenicity; substrate affinity; Magnaporthe oryzae
-
Impact of Oil Bodies on Structure, Rheology and Function of Acid-Mediated Soy Protein Isolate Gels
作者：Liu, Songbin;Zhang, Yi;Liu, Songbin;Zhao, Zhihao;Zhou, Pengfei;Deng, Yuanyuan;Liu, Guang;Li, Ping;Zeng, Jiarui;Zhang, Mingwei
关键词：acid-mediation; emulsion-filled gels; microstructure; oil bodies; soy protein isolate
-
Selective adsorption of volatile compounds of oyster peptides by V-type starch for effective deodorization
作者：Dai, Yaolin;Ren, Zhongyang;Zhang, Yucang;Weng, Wuyin;Shi, Linfan;Li, Ping;Ren, Zhongyang;Weng, Wuyin;Shi, Linfan
关键词：V-type starch; Oyster peptide; Off-odors; Selective adsorption; Deodorization
