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A Review of Emerging Goose Astrovirus Causing Gout

文献类型： 外文期刊

作者： Liu, Chenggang 1 ; Sun, Minhua 1 ; Liao, Ming 1 ;

作者机构： 1.Guangdong Acad Agr Sci, Inst Anim Hlth, Guangzhou 510640, Peoples R China

2.Minist Agr & Rural Affairs, Key Lab Prevent & Control Avian Influenza & Other, Guangzhou 510640, Peoples R China

3.Key Lab Livestock Dis Prevent Guangdong Prov, Guangzhou 510640, Peoples R China

4.Shanwei Acad Agr Sci, Shanwei, Peoples R China

期刊名称：BIOMED RESEARCH INTERNATIONAL （ 影响因子：3.246； 五年影响因子：3.767 ）

ISSN： 2314-6133

年卷期： 2022 年 2022 卷

页码：

收录情况： SCI

摘要： In recent years, an infection in geese caused by goose astrovirus (GAstV) has repeatedly occurred in coastal areas of China and rapidly spread to inland provinces. The infection is characterized by joint and visceral gout and is fatal. The disease has caused huge economic losses to China's goose industry. GAstV is a nonenveloped, single-stranded, positive-sense RNA virus. As it is a novel virus, there is no specific classification. Here, we review the current understanding of GAstV. The virus structure, isolation, diagnosis and detection, innate immune regulation, and transmission route are discussed. In addition, since GAstV can cause gout in goslings, the possible role of GAstV in gout formation and uric acid metabolism is discussed. We hope that this review will inform researchers to rapidly develop effective methods to prevent and treat this disease.

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