文献类型： 外文期刊
作者： Fu, Junjie 1 ; Liu, Jie 1 ; Zou, Xian 2 ; Deng, Ming 1 ; Liu, Guangbin 1 ; Sun, Baoli 1 ; Guo, Yongqing 1 ; Liu, Dewu 1 ; Li, Yaokun 1 ;
作者机构： 1.South China Agr Univ, Coll Anim Sci, Guangzhou 510642, Peoples R China
2.Guangdong Acad Agr Sci, Inst Anim Sci, State Key Lab Livestock & Poultry Breeding, Guangdong Key Lab Anim Breeding & Nutr, Guangzhou 510640, Peoples R China
3.South China Agr Univ, Natl Local Joint Engn Res Ctr Livestock & Poultry, Guangzhou 510642, Peoples R China
期刊名称：SCIENTIFIC REPORTS （ 影响因子：3.8； 五年影响因子：4.3 ）
ISSN： 2045-2322
年卷期： 2024 年 14 卷 1 期
页码：
收录情况： SCI
摘要： The progression of muscle development is a pivotal aspect of animal ontogenesis, where miRNA and mRNA exert substantial influence as prominent players. It is important to understand the molecular mechanisms involved in skeletal muscle development to enhance the quality and yield of meat produced by Leizhou goats. We employed RNA sequencing (RNA-SEQ) technology to generate miRNA-mRNA profiles in Leizhou goats, capturing their developmental progression at 0, 3, and 6 months of age. A total of 977 mRNAs and 174 miRNAs were found to be differentially expressed based on our analysis. Metabolic pathways, calcium signaling pathways, and amino acid synthesis and metabolism were found to be significantly enriched among the differentially expressed mRNA in the enrichment analysis. Meanwhile, we found that among these differentially expressed mRNA, some may be related to muscle development, such as MYL10, RYR3, and CSRP3. Additionally,, we identified five muscle-specific miRNAs (miR-127-3p, miR-133a-3p, miR-193b-3p, miR-365-3p, and miR-381) that consistently exhibited high expression levels across all three stages. These miRNAs work with their target genes (FHL3, SESN1, PACSIN3, LMCD1) to regulate muscle development. Taken together, our findings suggest that several miRNAs and mRNAs are involved in regulating muscle development and cell growth in goats. By uncovering the molecular mechanisms involved in muscle growth and development, these findings contribute valuable knowledge that can inform breeding strategies aimed at enhancing meat yield and quality in Leizhou goats.
- 相关文献
作者其他论文 更多>>
-
Achieving Optimal Transfection Conditions in Chicken Primordial Germ Cells Under Feeder- and Serum-Free Medium
作者：Zhao, Zhifeng;Zou, Xian;Zhu, Ying;He, Yanhua;Jebessa, Endashaw;Ji, Jian;Chen, Peng;Luo, Chenglong;Zhang, Jiannan
关键词：primordial germ cell; feeder free; electroporation; transfection efficiency; CRISPR/Cas 9
-
Synergy of genetics and lipid metabolism driving feed utilization efficiency in chickens
作者：Guo, Xiaoli;Sun, Jia;Zou, Xian;Ji, Jian;Qu, Hao;Shu, Dingming;Luo, Chenglong;Guo, Xiaoli;Sun, Jia;Zou, Xian;Ji, Jian;Qu, Hao;Shu, Dingming;Luo, Chenglong;Guo, Xiaoli;Sun, Jia;Zou, Xian;Ji, Jian;Qu, Hao;Shu, Dingming;Luo, Chenglong;Li, Jianbo;Li, Xiaochang;Li, Xiaochang
关键词：Chicken; RFI; Genetics; Lipid metabolism; Multiomics
-
Single-cell RNA-seq offer new insights into the cell fate decision of the primordial germ cells
作者：Zou, Xian;He, Yanhua;Zhao, Zhifeng;Qu, Hao;Liu, Zijing;Chen, Peng;Ji, Jian;Zhao, Haoyi;Shu, Dingming;Luo, Chenglong;Zou, Xian;He, Yanhua;Zhao, Zhifeng;Qu, Hao;Liu, Zijing;Chen, Peng;Ji, Jian;Zhao, Haoyi;Shu, Dingming;Luo, Chenglong;Zou, Xian;He, Yanhua;Zhao, Zhifeng;Qu, Hao;Liu, Zijing;Chen, Peng;Ji, Jian;Zhao, Haoyi;Shu, Dingming;Luo, Chenglong;Li, Jianbo
关键词：PGCs; Single-cell RNA-seq; Cell cycle; Small molecule; Proliferation; High efficiency
-
Invasion mechanisms of Eimeria coccidian and host immune responses in chicken intestine_A review
作者：Jebessa, Endashaw;Zou, Xian;Berihulay, Haile;He, Yanhua;Chuxiao, Lin;Zhao, Zhifeng;Qu, Hao;Chen, Peng;Ji, Jian;Luo, Chenglong;Jebessa, Endashaw;Nie, Qinghua;Berihulay, Haile;Ayalew, Wondossen;Bello, Semiu Folaniyi;Nie, Qinghua;Nie, Qinghua
关键词：Coccidian; Eimeria; Invading; Host immune; Chicken intestinal
-
Refining polyploid breeding in sweet potato through allele dosage enhancement
作者：Zhang, Xiangbo;Tang, Chaochen;Jiang, Bingzhi;Zhang, Rong;Yao, Zhufang;Huang, Lifei;Luo, Zhongxia;Zou, Hongda;Yang, Yiling;Wang, Zhangying;Li, Ming;Li, Ming;Wu, Yaoyao;Wu, Minyi;Chen, Ao;Hou, Xingliang;Liu, Xu;Wu, Minyi;Chen, Ao;Hou, Xingliang;Liu, Xu;Wu, Shan;Fei, Zhangjun;Fei, Zhangjun;Fu, Junjie
关键词：
-
The effects of boar seminal plasma extracellular vesicles on sperm fertility
作者：Xu, Zhiqian;Xie, Yanshe;Wu, Changhua;Gu, Ting;Zhang, Xianwei;Yang, Jie;Yang, Huaqiang;Zheng, Enqin;Huang, Sixiu;Xu, Zheng;Li, Zicong;Cai, Gengyuan;Liu, Dewu;Hong, Linjun;Wu, Zhenfang;Xu, Zhiqian;Xie, Yanshe;Wu, Changhua;Gu, Ting;Zhang, Xianwei;Yang, Jie;Yang, Huaqiang;Zheng, Enqin;Huang, Sixiu;Xu, Zheng;Li, Zicong;Cai, Gengyuan;Liu, Dewu;Hong, Linjun;Wu, Zhenfang;Xu, Zhiqian;Wu, Zhenfang;Hong, Linjun;Wu, Zhenfang
关键词：Seminal plasma extracellular vesicles; Proteomics; EZRIN; Sperm; Fertility
-
Identification of functional circRNAs regulating ovarian follicle development in goats
作者：Liu, Jie;Feng, Guanghang;Guo, Conghui;Li, Zhihan;Liu, Dewu;Liu, Guangbin;Sun, Baoli;Guo, Yongqing;Deng, Ming;Li, Yaokun;Zou, Xian;Liu, Jie;Feng, Guanghang;Guo, Conghui;Li, Zhihan;Liu, Dewu;Liu, Guangbin;Sun, Baoli;Guo, Yongqing;Deng, Ming;Li, Yaokun;Liu, Jie;Feng, Guanghang;Guo, Conghui;Li, Zhihan;Liu, Dewu;Liu, Guangbin;Sun, Baoli;Guo, Yongqing;Deng, Ming;Li, Yaokun
关键词：Leizhou goat; Follicular development; circCFAP20DC; Reproduction; RNA sequencing
