Evaluation of the efficacy of chlorogenic acid in reducing small intestine injury, oxidative stress, and inflammation in chickens challenged with Clostridium perfringens type A
文献类型： 外文期刊
作者： Zhang, Xinheng 1 ; Zhao, Qiqi 1 ; Ci, Xiaotong 1 ; Chen, Sheng 1 ; Xie, Zi 1 ; Li, Hongxin 1 ; Zhang, Huanmin 6 ; Chen, F 1 ;
作者机构： 1.South China Agr Univ, Coll Anim Sci, Lingnan Guangdong Lab Modern Agr, Guangzhou 510642, Peoples R China
2.Minist Agr, Guangdong Prov Key Lab Agroanim Genom & Mol Breed, Guangzhou 510642, Peoples R China
3.Minist Agr, Key Lab Chicken Genet Breeding & Reprod, Guangzhou 510642, Peoples R China
4.Guangdong Engn Res Ctr Vector Vaccine Anim Virus, Guangzhou 510642, Peoples R China
5.South China Collaborat Innovat Ctr Poultry Dis Co, Guangzhou 510642, Peoples R China
6.ARS, Avian Dis & Oncol Lab, USDA, E Lansing, MI 48823 USA
关键词： C. perfringens type A; chlorogenic acid; intestinal injury; oxidative stress; inflammation
期刊名称：POULTRY SCIENCE （ 影响因子：3.352； 五年影响因子：3.679 ）
ISSN：
年卷期： 2020 年 99 卷 12 期
页码：
收录情况： SCI
摘要： The goal of the study was testing the effects of chlorogenic acid (CA) supplementation on small intestine healthiness, growth performance, oxidative stress, inflammatory response, and blood biochemical indices in specific-pathogen-free (SPF) chickens after infection with Clostridium perfringens (CP) type A. In this study, 324 1-day-old male SPF chickens were randomly distributed into 6 groups: control group; CA group; CP infection group; CA + CP group; antibiotic group; antibiotic + CP group. All 1-day-old chickens were fed with CA or antibiotic in corresponding treatment group for 13 d. On the 14 d, the chickens in corresponding infection group were challenged with CP type A for 3 d. Samples in each group were collected when the chickens were 17 and 21 d old. This study proves for the first time that CA, a Chinese herbal medicine, can effectively improve growth performance, inhibit small intestine structural damage, improve antioxidant capacity, inhibit damage to ileal mucosal layer construction and tight junctions, inhibit inflammatory cytokines, and ameliorate blood biochemical indices. Therefore, this study provides data for CA being able to effectively alleviate small intestine damage caused by CP type A infection in chickens.
- 相关文献
作者其他论文 更多>>
-
Analysis of metagenome and metabolome disclosed the mechanisms of Dendrobium officinale polysaccharide on DSS-induced ulcerative colitis-affected mice
作者：Zeng, Xiaona;Tang, Shengqiu;Dong, Xiaoying;Zeng, Xiaona;Dong, Mengyue;Shao, Runlin;Liu, Ruiheng;Li, Tong;Zhang, Xinheng;Xie, Qingmei;Zeng, Xiaona;Dong, Mengyue;Shao, Runlin;Liu, Ruiheng;Li, Tong;Zhang, Xinheng;Xie, Qingmei;Zeng, Xiaona;Tang, Shengqiu;Dong, Xiaoying;Zeng, Xiaona;Dong, Mengyue;Shao, Runlin;Liu, Ruiheng;Li, Tong;Zhang, Xinheng;Xie, Qingmei;Zeng, Xiaona;Dong, Mengyue;Shao, Runlin;Liu, Ruiheng;Li, Tong;Zhang, Xinheng;Xie, Qingmei;Wong, Yung Hou;Wong, Yung Hou
关键词：Dendrobium officinale polysaccharide; Ulcerative colitis (UC); Metagenome; Metabolome
-
Exosomal circ_CCDC7/gga-miR-6568-3p/Pax7 axis accelerates the differentiation of chicken embryonic stem cells infected with subgroup J avian leukosis virus
作者：Zeng, Xiaona;Wang, Ruonan;Chen, Sheng;Chen, Liyi;Li, Yajuan;Shao, Guanming;Zhang, Xinheng;Xie, Qingmei;Zeng, Xiaona;Wang, Ruonan;Liao, Liqin;Chen, Sheng;Kong, Jie;Chen, Liyi;Li, Yajuan;Shao, Guanming;Zhang, Xinheng;Xie, Qingmei;Zeng, Xiaona;Tang, Shengqiu;Dong, Xiaoying;Xie, Qingmei;Zeng, Xiaona;Wang, Ruonan;Liao, Liqin;Chen, Sheng;Kong, Jie;Chen, Liyi;Li, Yajuan;Shao, Guanming;Zhang, Xinheng;Xie, Qingmei;Zeng, Xiaona;Wang, Ruonan;Liao, Liqin;Chen, Sheng;Kong, Jie;Chen, Liyi;Li, Yajuan;Shao, Guanming;Zhang, Xinheng;Xie, Qingmei;Zeng, Xiaona;Tang, Shengqiu;Li, Yajuan;Wong, Yung Hou;Wong, Yung Hou
关键词：circRNA; ALV-J; chicken embryonic stem cell
-
Resveratrol Enhances Antioxidant and Anti-Apoptotic Capacities in Chicken Primordial Germ Cells through m6A Methylation: A Preliminary Investigation
作者：Qiao, Yanzhao;Xiao, Gengsheng;Zhang, Xinheng;Kong, Jie;Xie, Qingmei;Qiao, Yanzhao;Xiao, Gengsheng;Zhang, Xinheng;Kong, Jie;Xie, Qingmei;Qiao, Yanzhao;Xiao, Gengsheng;Bu, Yonghui;Zhang, Xinheng;Kong, Jie;Xie, Qingmei;Qiao, Yanzhao;Xiao, Gengsheng;Zhang, Xinheng;Kong, Jie;Xie, Qingmei;Zhu, Xiaohua;Wen, Jun;Bai, Yinshan;Zhu, Xiaohua;Wen, Jun;Bai, Yinshan
关键词：primordial germ cells; resveratrol; antioxidant; apoptosis; m6A methylation
-
Small RNAs contribute to citrus Huanglongbing tolerance by manipulating methyl salicylate signaling and exogenous methyl salicylate primes citrus groves from emerging infection
作者：Cheng, Baoping;Peng, Aitian;Cheng, Baoping;Peng, Aitian;Xu, Le;Bilal, Muhammad Saqib;Huang, Qing;Niu, Dongdong;Ma, Hongyu;Zhou, Shaoxia;Zhao, Hongwei;Xu, Le;Bilal, Muhammad Saqib;Huang, Qing;Niu, Dongdong;Ma, Hongyu;Zhou, Shaoxia;Zhao, Hongwei;Wei, Guo;Chen, Feng;Zeng, Liang;Lin, Hong;Baig, Ayesha;Wang, Xuefeng;Zou, Xiuping
关键词：microRNA; immunity; methyl salicylate; community immunity; gene silencing; Shatangju
-
Critical role for ribonucleoside-diphosphate reductase subunit M2 in ALV-J-induced activation of Wnt/β-catenin signaling via interaction with P27
作者：Tang, Shuang;Leng, Mei;Tan, Chen;Zhu, Lin;Pang, Yanling;Zhang, Xinheng;Lin, Wencheng;Chang, Yung-Fu
关键词：ALV-J; RRM2; Wnt/beta-catenin signaling; replication
-
Molecular characterization, complete genome sequencing, and pathogenicity of Novel Duck Reovirus from South Coastal Area in China
作者：Kong, Jie;Shao, Guanming;Zhang, Yukun;Wang, Jinfeng;Xie, Zi;Feng, Keyu;Zhang, Xinheng;Xie, Qingmei;Kong, Jie;Shao, Guanming;Zhang, Yukun;Wang, Jinfeng;Xie, Zi;Feng, Keyu;Zhang, Xinheng;Xie, Qingmei;Kong, Jie;Shao, Guanming;Zhang, Yukun;Wang, Jinfeng;Xie, Zi;Feng, Keyu;Zhang, Xinheng;Xie, Qingmei;Shao, Guanming;Feng, Keyu;Feng, Keyu;Kong, Jie;Shao, Guanming;Zhang, Yukun;Wang, Jinfeng;Xie, Zi;Feng, Keyu;Zhang, Xinheng;Xie, Qingmei
关键词：Novel Duck Reovirus; isolated; complete genome; phylogenetic analysis; pathogenicity
-
Analysis of long noncoding RNAs and messenger RNAs expression profiles in the hearts of mice with acute viral myocarditis
作者：Xue, Yimin;Chen, Mingguang;Zeng, Lijuan;Fan, Qiaolian;Ke, Jun;Zhang, Jiuyun;Chen, Feng;Ke, Jun;Zhang, Jiuyun;Chen, Feng;Zheng, Chunfu;Zheng, Chunfu;Chen, Feng
关键词：acute viral myocarditis; coxsackievirus B3; long noncoding RNAs; messenger RNAs; RNA sequencing
