文献类型： 外文期刊
作者： Shen, Guoqing 1 ; Zhang, Xiao 1 ; Gong, Jie 1 ; Wang, Yang 1 ; Huang, Pengdan 2 ; Shui, Yan 2 ; Xu, Zenghong 2 ; Shen, Hu 1 ;
作者机构： 1.Nanjing Agr Univ, Wuxi Fisheries Coll, Nanjing 210095, Peoples R China
2.Chinese Acad Fishery Sci, Freshwater Fisheries Res Ctr, Key Lab Freshwater Fisheries & Germplasm Resource, Minist Agr, 9 Shanshui East Rd, Wuxi 214081, Jiangsu, Peoples R China
期刊名称：SCIENTIFIC REPORTS （ 影响因子：4.379； 五年影响因子：5.133 ）
ISSN： 2045-2322
年卷期： 2020 年 10 卷 1 期
页码：
收录情况： SCI
摘要： Each year from April to May, high mortality rates are reported in red swamp crayfish (Procambarus clarkii) cultured in Jiangsu and other regions, in China, and this phenomenon has come to be known as "Black May" disease (BMD). Therefore, in order to investigate the possible causes of this disease, this study gathered BMD-affected P. clarkii samples and performed transcriptome analysis on hepatopancreas, gill, and muscle tissues. A total of 19,995,164, 149,212,804, and 222,053,848 clean reads were respectively obtained from the gills, muscle, and hepatopancreas of BMD-affected P. clarkii, and 114,024 unigenes were identified. The number of differentially expressed genes (DEGs) in gill, muscle, and hepatopancreas was 1703, 964, and 476, respectively. GO and KEGG enrichment analyses of the DEGs were then conducted. Based on KEGG pathway enrichment analysis, the most significantly differentially expressed pathways were mainly those involved with metabolism, human disease, and cellular processes. Further analysis of the significantly DEGs revealed that they were mainly related to the mitochondrial-mediated apoptosis pathway and that the expression of these DEGs was mostly down-regulated. Moreover, the expression of genes related to immune and metabolism-related pathways was also significantly down-regulated, and these significantly-inhibited pathways were the likely causes of P. clarkii death. Therefore, our results provide a basis for the identification of BMD causes.
- 相关文献
作者其他论文 更多>>
-
Endoplasmic reticulum stress and Ca2+ dysregulation in response to ammonia nitrogen exposure could be alleviated by dietary fermented mulberry leaf meal in Megalobrama amblycephala
作者：Jiang, Wenqiang;Lin, Yan;Lu, Siyue;Gu, Zhengyan;Shen, Huaishun;Ge, Xianping;Miao, Linghong;Jiang, Wenqiang;Qian, Linjie;Mu, Qiaoqiao;Shen, Huaishun;Ge, Xianping;Miao, Linghong
关键词：Fermented mulberry leaf meal; Ammonia nitrogen stress; Endoplasmic reticulum stress; Ca 2+transport; Autophagy
-
Responses of adult crayfish to macro-nutrients intake alteration during juvenile stage on metabolism and intestinal microbiota
作者：Shui, Yan;Su, Shengyan;Xu, Zenghong;Su, Shengyan;Xu, Zhiqiang
关键词：Procambarus clarkii; Programming effects; Digestive enzymes; Nutrient use; Intestinal microbiota
-
Mulberry Leaf Polysaccharides Attenuate Oxidative Stress Injury in Peripheral Blood Leukocytes by Regulating Endoplasmic Reticulum Stress
作者：Jiang, Wenqiang;Qian, Linjie;Shen, Huaishun;Ge, Xianping;Miao, Linghong;Lin, Yan;Lu, Siyue;Shen, Huaishun;Ge, Xianping;Miao, Linghong
关键词：mulberry leaf polysaccharides; peripheral blood leukocytes; oxidative damage; endoplasmic reticulum stress; Megalobrama amblycephala
-
An investigation into the wound-healing mechanism in gill injuries of varying severity in the freshwater mussel Solenaia oleivora (Heude, 1877)
作者：Wen, Lujie;Geng, Kaixiang;Jin, Wu;Chen, Wanwen;Xu, Dongpo;Shen, Huaishun;Wen, Haibo;Ma, Xueyan;Lv, Guohua;Jin, Wu;Xu, Dongpo;Shen, Huaishun;Wen, Haibo;Ma, Xueyan;Lv, Guohua;Jin, Wu;Xu, Dongpo;Shen, Huaishun;Wen, Haibo;Shen, Huaishun;Wen, Haibo
关键词：Solenaia oleivora; RNA-seq; Immunity; Epithelialization; Wound-healing
-
The Application of Moringa oleifera Leaf Meal and Its Fermentation Products in the Diet of Megalobrama amblycephala Juveniles
作者：Jiang, Wenqiang;Qian, Linjie;Zhao, Yongfeng;Yang, Yang;Shen, Huaishun;Ge, Xianping;Miao, Linghong;Zhao, Yongfeng;Lin, Yan;Shen, Huaishun;Ge, Xianping;Miao, Linghong
关键词：Moringa oleifera leaf meal; fermentation; lipid metabolism; antioxidant; anti-inflammatory
-
Genome-wide evolutionary signatures of climate adaptation in spotted sea bass inhabiting different latitudinal regions
作者：Chen, Baohua;Zhou, Zhixiong;Shi, Yue;Gong, Jie;Li, Chengyu;Zhou, Tao;Chen, Baohua;Zhou, Zhixiong;Shi, Yue;Gong, Jie;Li, Chengyu;Xu, Peng;Zhou, Tao;Xu, Peng;Li, Yun;Zhang, Dianchang
关键词：climate adaptation; evolutionary signatures; population structure; spotted sea bass
-
Pathogenicity and detection method based on interferon release assay of Mycobacteria marinum isolated from sturgeon
作者：Xie, Meng;Deng, Dan;Li, Qian;Zhang, Xiao;Luo, Kai;Zhou, Jiang;Xu, Qiaoqing;Li, Chenghua;Xu, Qiaoqing;Wang, Bei;Xu, Qiaoqing;Wei, Qiwei;Zhang, Shuhuan
关键词：Chinese sturgeon; Mycobacterium marinum; Antimicrobial-response; Disease detection
