文献类型： 外文期刊
作者： Liu, Manli 1 ; Wan, Zhongyi 1 ; Yang, Sumei 2 ; Liu, Fang 1 ; Yang, Xiliang 2 ; Wu, Zhaoyuan 1 ; Zhang, Yanni 1 ; Wang, K 1 ;
作者机构： 1.Hubei Acad Agr Sci, Hubei Biopesticide Engn Res Ctr, Wuhan, Peoples R China
2.Wuhan Univ Sci & Technol, Dept Pharm, Coll Med, Wuhan, Peoples R China
期刊名称：JOURNAL OF ANTIBIOTICS （ 影响因子：2.668； 五年影响因子：2.301 ）
ISSN： 0021-8820
年卷期：
页码：
收录情况： SCI
摘要： Two new dipimprinine alkaloids dipimprinine E (1) and dipimprinine F (2) were isolated from Streptomyces sp. 44414B. The structure was elucidated by extensive spectroscopic analysis, including ESI-MS, HR-MS, and 1D and 2D NMR experiments. Dipimprinines F (2) showed cytotoxic activities against three tumor cell lines, including A-875, Hep G2, and H-460, with IC50 values of 26.4, 0.5, and 9.0 mu g ml(-1), respectively.
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