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SARS-CoV-2: An Updated Review Highlighting Its Evolution and Treatments

文献类型: 外文期刊

作者: Zhang, Xirui 1 ; Yuan, Hao 1 ; Yang, Zipeng 1 ; Hu, Xiaoyu 1 ; Mahmmod, Yasser S. 3 ; Zhu, Xiaojing 1 ; Zhao, Cuiping 5 ; Zhai, Jingbo 6 ; Zhang, Xiu-Xiang 1 ; Luo, Shengjun 2 ; Wang, Xiao-Hu 2 ; Xue, Mengzhou 7 ; Zheng, Chunfu 2 ; Yuan, Zi-Guo 1 ;

作者机构: 1.South China Agr Univ, Coll Vet Med, Guangdong Prov Key Lab Zoonosis Prevent & Control, Guangzhou 510642, Peoples R China

2.Guangdong Acad Agr Sci, Inst Anim Hlth, Key Lab Livestock Dis Prevent Guangdong Prov, Sci Observat & Expt Stn Vet Drugs & Diagnost Tech, Guangzhou 510640, Peoples R China

3.Zagazig Univ, Fac Vet Med, Dept Anim Med, Infect Dis, Zagazig 44511, Egypt

4.Al Ain Mens Coll, Higher Coll Technol, Vet Sci Div, Abu Dhabi, U Arab Emirates

5.80 Army Hosp Chinese Peoples Liberat Army, Weifang 261021, Peoples R China

6.Inner Mongolia Minzu Univ, Univ Inner Mongolia Autonomous Reg, Med Coll, Key Lab Zoonose Prevent & Control, Tongliao 028000, Peoples R China

7.Zhengzhou Univ, Dept Cerebrovascular Dis, Affiliated Hosp 2, Zhengzhou 450014, Peoples R China

8.Univ Calgary, Dept Microbiol Immunol & Infect Dis, Calgary, AB T2N 4N1, Canada

关键词: SARS-CoV-2; COVID-19; evolution; vaccines; drug; treatments

期刊名称:VACCINES ( 影响因子:4.961; 五年影响因子:5.325 )

ISSN:

年卷期: 2022 年 10 卷 12 期

页码:

收录情况: SCI

摘要: Since the SARS-CoV-2 outbreak, pharmaceutical companies and researchers worldwide have worked hard to develop vaccines and drugs to end the SARS-CoV-2 pandemic. The potential pathogen responsible for Coronavirus Disease 2019 (COVID-19), SARS-CoV-2, belongs to a novel lineage of beta coronaviruses in the subgenus arbovirus. Antiviral drugs, convalescent plasma, monoclonal antibodies, and vaccines are effective treatments for SARS-CoV-2 and are beneficial in preventing infection. Numerous studies have already been conducted using the genome sequence of SARS-CoV-2 in comparison with that of other SARS-like viruses, and numerous treatments/prevention measures are currently undergoing or have already undergone clinical trials. We summarize these studies in depth in the hopes of highlighting some key details that will help us to better understand the viral origin, epidemiology, and treatments of the virus.

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