Metabolomic profiles and health-promoting functions of Camellia drupifera mature-seeds were revealed relate to their geographical origins using comparative metabolomic analysis and network pharmacology approach
文献类型： 外文期刊
作者： Xia, Tengfei 1 ; Xiong, Zijun 3 ; Sun, Xiuxiu 1 ; Chen, Jiali 1 ; Wang, Chunmei 1 ; Chen, Yeguang 1 ; Zheng, Daojun 1 ;
作者机构： 1.Hainan Acad Agr Sci, Inst Trop Hort Res, Key Lab Trop Special Econ Plant Innovat & Utilizat, Natl Germplasm Resource Chengmai Observat & Expt S, Haikou 571100, Peoples R China
2.Hainan Acad Agr Sci, Sanya Inst, Sanya 572025, Peoples R China
3.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China
关键词： Camellia drupifera mature-seeds; Comparative metabolomic analysis; Network pharmacology approach; Health-promoting; Differential metabolites
期刊名称：FOOD CHEMISTRY （ 影响因子：8.8； 五年影响因子：8.6 ）
ISSN： 0308-8146
年卷期： 2023 年 426 卷
页码：
收录情况： SCI
摘要： To insight into the chemical components and their health-promoting function of Camellia drupifera mature-seeds (CMS) in Hainan and Liangguang, UPLC-MS/MS- and HS-SPME/GC-MS-based metabolomic analyses and network pharmacology approaches were combined preformed to Camellia drupifera mature-seeds samples (CMSSs). Totally, 1057 metabolites were identified, of which 76 and 99 metabolites were annotated as key active ingredients in Traditional Chinese Medicines and the active pharmaceutical ingredients for seven human diseaseresistance, respectively. Comparative analysis revealed different metabolomic profiles of CMSSs from Hainan and Liangguang. KEGG annotation and enrichment analysis showed secondary metabolic pathways, especially "flavone and flavonol biosynthesis", were played important roles. Finally, 22 metabolites that only detected in CMSSs from Hainan or Liangguang were explored as potential indicators to separate CMS from Hainan out of Liangguang. Our findings enhanced the understanding of chemical compositions of CMS and provided valuable information for the healthy development of oil-tea Camellia industry in Hainan.
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