Effects of single and combined exposure to BDE-47 and PFOA on distribution, bioaccumulation, and toxicity in blue mussel (Mytilus galloprovincialis)
文献类型： 外文期刊
作者： Geng, Qianqian 1 ; Guo, Mengmeng 1 ; Wu, Haiyan 1 ; Peng, Jixing 1 ; Zheng, Guanchao 1 ; Liu, Xiaoyu 1 ; Zhai, Yuxiu 1 ; Tan, Zhijun 1 ;
作者机构： 1.Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Key Lab Testing & Evaluat Aquat Prod Safety & Qua, Minist Agr & Rural Affairs, Qingdao 266071, Peoples R China
2.Shanghai Ocean Univ, Coll Food Sci & Technol, Shanghai 201306, Peoples R China
3.Pilot Natl Lab Marine Sci & Technol Qingdao, Qingdao 266071, Peoples R China
4.Dalian Polytech Univ, Collaborat Innovat Ctr Seafood Deep Proc, Dalian 116034, Peoples R China
关键词： New persistent organic pollutants; Bioconcentration; Combined toxicity; Biomarker; Blue mussel
期刊名称：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY （ 影响因子：7.129； 五年影响因子：7.284 ）
ISSN： 0147-6513
年卷期： 2021 年 228 卷
页码：
收录情况： SCI
摘要： The contamination of 2,2',4,4'-Tetrabrmodiphenyl ether (BDE-47) and perfluorooctanoic acid (PFOA) has drawn a worldwide attention over the risks in ecological and food safety. In this work, blue mussel (Mytilus galloprp-vincialis) was employed to investigate the combined effects of BDE-47 (10 ng mL(-1)) and PFOA (100 ng mL(-1)) on tissue distribution, accumulation, elimination, and toxicity. Results suggested that BDE-47 and PFOA accumu-lated mostly in digestive gland, followed by gills and gonad, and M. galloprovincialis displayed higher accumu-lation capacity to BDE-47 than PFOA. Co-exposure treatment reduced the accumulation of BDE-47, and enhanced the accumulation of PFOA. Furthermore, biochemical and histopathological tests revealed that the aggravated toxicity in co-exposure groups was mainly attributed to the oxidative stress and damage of tissue structure. This work could be helpful to get a better understanding of the combined behaviors and cumulative risks of BDE-47 and PFOA in marine ecosystem.
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