文献类型： 外文期刊
作者： Li, Junxuan 1 ; Yang, Daji 1 ; Wang, Hua 2 ; Zhu, Baofu 1 ; Cao, Hua 1 ;
作者机构： 1.Guangdong Pharmaceut Univ, Sch Chem & Chem Engn, Zhongshan 528458, Peoples R China
2.Hubei Acad Agr Sci, Inst Plant Protect & Soil Sci, Nanhu Rd 6, Wuhan 430064, Hubei, Peoples R China
关键词： Aminoalkyl; Indolizines; Zinc; [3+2]-Annulation
期刊名称：EUROPEAN JOURNAL OF ORGANIC CHEMISTRY （ 影响因子：3.021； 五年影响因子：2.79 ）
ISSN： 1434-193X
年卷期： 2019 年 2019 卷 39 期
页码：
收录情况： SCI
摘要： An efficient Zn-catalyzed [3+2]-annulation strategy for the synthesis of aminoalkyl indolizines has been developed. The three-component domino reaction of 2-(pyridin-2-yl)acetates, ynals and amines proceeds smoothly with high efficiency to afford the indolizines in good yields. This transformation may facilitate the development of new synthetic methods for the efficient and sustainable construction of aminoalkyl indolizines in an atom-economic way from simple, abundant starting materials.
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