The combination between NCSTN gene copy number variation and growth traits in Chinese cattle
文献类型： 外文期刊
作者： Yao, Yu-Fei 1 ; Lyu, Shijie 2 ; Wang, Xianwei 3 ; Zhang, Zijing 2 ; Qu, Kaixing 4 ; Xu, Jiawei 1 ; Cai, Cuicui 5 ; Li, Zh 1 ;
作者机构： 1.Northwest A&F Univ, Coll Anim Sci & Technol, 22 Xinong Rd, Yangling 712100, Shaanxi, Peoples R China
2.Henan Acad Agr Sci, Inst Anim Husb & Vet Sci, Zhengzhou, Henan, Peoples R China
3.Henan Prov Anim Husb Gen Stn, Zhengzhou, Henan, Peoples R China
4.Yunnan Acad Grassland & Anim Sci, Kunming 650212, Yunnan, Peoples R China
5.Ningxia Acad Agr & Forestry Sci, Guyuan, Ningxia, Peoples R China
关键词： NCSTN gene; copy number variation (CNV); Chinese cattle; growth traits; association analysis
期刊名称：ANIMAL BIOTECHNOLOGY （ 影响因子：2.282； 五年影响因子：1.702 ）
ISSN： 1049-5398
年卷期：
页码：
收录情况： SCI
摘要： Copy number variation (CNV) has been used as an important source of phenotypic and genetic diversity in recent years. Nicastrin (NCSTN) gene is usually attached to human diseases such as Alzheimer's disease, and Acne inversa. However, there are no essays about the NCSTN gene combining with cattle breeds. In our study, we discovered different distributions of NCSTN gene copy number and associated it with phenotypic traits in four Chinese yellow cattle breeds (XN, PN, QC and YL). The result turned out that the CNV of the NCSTN gene was associated with several growth traits, such as cannon circumference, chest girth and rump length (p < 0.05). In general, we revealed the eminence over CNV of NCSTN gene and economic traits, suggesting that the CNV of the NCSTN gene can be considered to be a promising molecular breeding marker of Chinese beef cattle.
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