文献类型： 外文期刊
作者： Su, Hong 1 ; Chen, Lu 1 ; Guo, Wenrui 1 ; Wang, Daqing 1 ; Dou, Aolei 1 ; Su, Jie 1 ; Yang, Yanyan 4 ; Tian, Ying 4 ; He, Tingyi 4 ; Wang, Caiyun 1 ; Du, Chenguang 1 ; Li, Haijun 1 ; Li, Xihe 5 ; Cao, Guifang 1 ; Song, Yongli 5 ; Bao, Fuxiang 3 ;
作者机构： 1.Inner Mongolia Agr Univ, Coll Vet Med, Hohhot, Peoples R China
2.Inst Inner Mongolia Autonomous Reg, Anim Embryo & Dev Engn Key Lab Higher Educ, Hohhot, Peoples R China
3.Inner Mongolia Autonomous Reg Key Lab Basic Vet Me, Hohhot, Peoples R China
4.Inner Mongolia Acad Agr & Anim Husb Sci, Inst Anim Husb, Hohhot, Peoples R China
5.Inner Mongolia Univ, Coll Life Sci, Inner Mongolia, Peoples R China
关键词： 16-day embryos; Hulunbuir short- tailed sheep; Ujumqin sheep; mRNA sequencing; Organogenesis
期刊名称：PAKISTAN JOURNAL OF ZOOLOGY （ 影响因子：0.5； 五年影响因子：0.6 ）
ISSN： 0030-9923
年卷期： 2024 年 56 卷 4 期
页码：
收录情况： SCI
摘要： Early embryonic development determines fetal and adult development. However, little is known about the specific development of the early Mongolian sheep embryo. We aim to analyze the differentially expressed genes (DEGs) between 16-day embryos of two breeds of Mongolian sheep, namely, Hulunbuir short-tailed sheep and Ujumqin sheep, by mRNA sequencing. A total of 2152 DEGs were identified. Significantly DEGs include WNT5A, WNT2, AXIN2, BMP5, TGFB2, and SMAD9, which are involved in multiple signaling pathways, and genes involved in digestion and absorption and cellular differentiation, such as DPP4, ACE2, PLPP1, CD22, CD44, TEC, and JAK1. In the pathway analysis, the development of Hulunbuir short-tailed sheep 16-day embryo H(E16) highlighted pathways primarily associated with cellular interactions and organogenesis. These pathways are critical for transcriptional control during early embryonic development, especially organ formation. Genes that sophisticate organs and body mechanisms, and genes associated with protein and fat digestion, hematopoietic stem cell lineage and osteoblast differentiation, are enriched during the development of the Ujumqin sheep 16-day embryo U(E16). Our work provides important complementary reference data for the study of early embryonic development in sheep.
- 相关文献
作者其他论文 更多>>
-
Whole-Genome Resequencing of Ujimqin Sheep Identifies Genes Associated with Vertebral Number
作者：Zhou, Chuanqing;Zhang, Yue;Ma, Teng;Cao, Guifang;Zhou, Chuanqing;Yang, Siqi;Song, Yongli;Zhang, Yong;Zuo, Yongchun;Wu, Dabala;Yang, Yanyan;Wang, Daqing;Li, Xiunan;Guo, Shuchun;Zhang, Yong
关键词：Ujimqin sheep; vertebral number; whole-genome resequencing; ABCD4 gene
-
Fat deposition and partitioning for meat production in cattle and sheep
作者：Liu, Shimin;Martin, Graeme B.;Yang, Yanyan;Luo, Hailing;Pang, Wenjie
关键词：Fat depot; Fat partition; Intramuscular fat; Feed ef ficiency; Bovine; Ovine
-
Exploring the formation mechanism of short-tailed phenotypes in animals using mutant mice with the TBXT gene c.G334T developed by CRISPR/Cas9
作者：Su, Hong;Zhi, Dafu;Wang, Daqing;Li, Xiunan;Cao, Guifang;Su, Hong;Zhi, Dafu;Wang, Daqing;Li, Xiunan;Cao, Guifang;Su, Hong;Zhi, Dafu;Li, Xiunan;Cao, Guifang;Yang, Yanyan;Wang, Daqing;Li, Xiunan;Song, Yongli
关键词：TBXT gene; CRISPR/Cas9; Short-tailed phenotype; Wnt signaling pathway
-
The ERβ-cAMP signaling pathway regulates estradiol-induced ovine oocyte meiotic arrest
作者：Yang, Bingxue;Zhao, Yufen;Yu, Kai;Weng, Yu;Du, Chenguang;Li, Haijun;Yang, Bingxue;Zhao, Yufen;Yu, Kai;Weng, Yu;Du, Chenguang;Li, Haijun;An, Yang;Yang, Yanyan;Yu, Boyang
关键词：Sheep; Cumulus-oocyte complex; 17 beta-estradiol; Cyclic adenosine monophosphate; Estrogen nuclear receptor
-
The Transcriptional Landscape of the Early Embryonic Developmental Biology in Hulunbuir Short-Tailed Sheep
作者：Su, Hong;Yang, Guang;Cao, Gui-Fang;Chen, Lu;Cao, Gui-Fang;Su, Hong;Chen, Lu;Yang, Guang;Cao, Gui-Fang;Wang, Da-Qing;Li, Xiu-Nan;Song, Yong-Li
关键词：Embryo of hulunbuir short-tailed sheep; Early embryonic developmental; Organogenesis; RNA-seq
-
The Impact of Novel BMPR1B Mutations on Litter Size in Short-Tailed Gobi Sheep and Larger-Tailed Ujimqin Sheep
作者：Bai, Yanyu;Cang, Ming;Tong, Bin;Wang, Shenyuan;Wu, Kaifeng;Zhang, Ming;Alatan, Suhe;Cao, Guifang;Jin, Hai;Li, Changqing
关键词：BMPR1B; litter size; Gobi short tail sheep; Ujimqin sheep; T/Brachyury
-
A Single-Cell Atlas of an Early Mongolian Sheep Embryo
作者：He, Tingyi;Guo, Wenrui;Su, Hong;Dou, Aolei;Chen, Lu;Ma, Teng;Liu, Moning;Su, Budeng;Qi, Wangmei;Li, Haijun;Mao, Wei;Wang, Xiumei;Cao, Guifang;He, Tingyi;Yang, Yanyan;Yang, Guang;Li, Xihe;Song, Yongli;Yang, Guang;Li, Xihe;Song, Yongli;Su, Jie
关键词：Mongolian sheep; embryo; scRNA-seq; Hippo signaling pathway
