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Long noncoding RNA and mRNA expression profiles following igf3 knockdown in common carp, Cyprinus carpio

文献类型: 外文期刊

作者: Song, Feibiao 1 ; Wang, Lanmei 2 ; Zhu, Wenbin 2 ; Dong, Zaijie 1 ;

作者机构: 1.Nanjing Agr Univ, Wuxi Fisheries Coll, Wuxi 214081, Jiangsu, Peoples R China

2.Chinese Acad Fishery Sci, Freshwater Fisheries Res Ctr, Key Lab Freshwater Fisheries & Germplasm Resource, Minist Agr & Rural Affairs, Wuxi 214081, Jiangsu, Peoples R China

期刊名称:SCIENTIFIC DATA ( 影响因子:6.444; 五年影响因子:9.051 )

ISSN:

年卷期: 2019 年 6 卷

页码:

收录情况: SCI

摘要: As a novel IGF system member, igf3 plays an important role in gonadal development of teleost fish. Although studies have reported the unusual expression of igf3 in fish gonad, whether the igf3 affects the expression of long noncoding RNAs (lncRNAs) in gonad remains unknown. In this study, an igf3 knockdown common carp (Cyprinus carpio) model was established by RNA interference. Then RNA sequencing of C. carpio gonad after igf3 knockdown was performed. A total of 327,169,410 and 306,305,018 clean reads were identified from control and igf3 dsRNA interference group, respectively. After a stringent filtering, RNA seq yielded 14199 lncRNA and 106932 mRNA transcripts with 124 and 353 differentially expressed lncRNAs and mRNAs. Our dataset provides an extensive resource for understanding the potential regulatory molecular mechanism of igf3 in early stage of gonadal development in C. carpio.

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