您好，欢迎访问江苏省农业科学院 机构知识库！
江苏省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Hesperetin and Hesperidin Improved beta-Carotene Incorporation Efficiency, Intestinal Cell Uptake, and Retinoid Concentrations in Tissues

文献类型： 外文期刊

作者： Nie, Meimei 1 ; Zhang, Zhongyuan 1 ; Liu, Chunquan 1 ; Li, Dajing 1 ; Huang, Wuyang 1 ; Liu, Chunju 1 ; Jiang, Ning 1 ;

作者机构： 1.Jiangsu Acad Agr Sci, Inst Agroprod Proc, Nanjing 210014, Jiangsu, Peoples R China

2.Nanjing Agr Univ, Coll Food & Technol, Nanjing 210095, Jiangsu, Peoples R China

3.Jiangsu Prov & Chinese Acad Sci, Inst Bot, Nanjing 210014, Jiangsu, Peoples R China

关键词： beta-carotene; bioaccessibility; citrus flavanone; absorption; Caco-2 cell

期刊名称：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY （ 影响因子：5.279； 五年影响因子：5.269 ）

ISSN： 0021-8561

年卷期： 2019 年 67 卷 12 期

页码：

收录情况： SCI

摘要： Dietary constituents can influence the bioavailability of carotenoids. This study investigated the effect of citrus flavanones on beta-carotene (Bc) bioavailability using four experimental models: in vitro digestion procedure, synthetic mixed micelles, Caco-2 cell monolayers, and gavage experiments in mice. The addition of hesperetin (Hes, 25 mu M) and hesperidin (Hes-G, 25 mu M) standards significantly increased the incorporation efficiency of the Bc standard to 68.7 +/- 3.6 and 75.2 +/- 7.5% (p < 0.05), respectively. However, the addition of naringenin (Nar, 25 mu M) and naringin (Nar-G, 25 mu M) standards significantly reduced the incorporation efficiency of Bc by 23.8 and 26.4%, respectively (p < 0.05). The increases in scavenger receptor class B type I (SR-BI) expression promoted by citrus flavanones played an important role in Bc cellular absorption in the Caco-2 cell model. Furthermore, after 3 days of gavage, four citrus flavanones (7.5 mg kg(-1) day(-1)) increased the retinoid concentrations in tissues; in contrast, after 7 days of gavage, Nar and Nar-G significantly decreased hepatic retinoid concentrations (p < 0.05). This finding suggested that the incorporation efficiency into micelles was the main step governing carotenoid bioavailability.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：江苏省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台