文献类型： 外文期刊
作者： He, Lili 1 ; Ji, Jingwen 1 ; Sun, Jian 1 ; Pengjuan, Zhou 1 ; Zhai, Lijuan 1 ; Tang, Dong 1 ; Mu, Yangxiu 1 ; Wang, Ling 1 ; Yang, Haikang 1 ; Ji, Jinbo 1 ; Iqbal, Zafar 1 ; Yang, Zhixiang 1 ;
作者机构： 1.Ningxia Acad Agr & Forestry Sci, Ningxia Ctr Organ Synth & Engn Technol, 590 Huanghe East Rd, Yinchuan 750002, Ningxia, Peoples R China
关键词： O -b; D -glucopyranosyl; L -ascorbic acid; AA-2bG; L -Ascorbic acid; Glycosylation; TBDPS
期刊名称：TETRAHEDRON LETTERS （ 影响因子：1.8； 五年影响因子：1.8 ）
ISSN： 0040-4039
年卷期： 2023 年 115 卷
页码：
收录情况： SCI
摘要： 2-O-b-D-glucopyranosyl-L-ascorbic acid (AA-2pG) provides a source of sustained release of ascorbic acid (vitamin C) upon a-glucosidase activity inside the human body, and is therefore an ingredient of cosmet-ics, food, and medicinal products. Commercial synthesis of the compound is highly demanded and is attempted from time to time, aimed at improved and commercially viable strategies. We synthesized the AA-2pG in five steps starting from ascorbic acid with a 31.4% overall yield. The synthetic steps do not need column purification except one, and the final product is pure enough to be utilized for applica-tion purposes. (c) 2022 Elsevier Ltd. All rights reserved.
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