An efficient and environment-friendly halogenation of imidazoheterocycles with Bu 4 NX (X = Cl, Br and I) using iodobenzene diacetate as oxidant
文献类型： 外文期刊
作者： Yang, Minghua 1 ; Shao, Yating 1 ; Zhang, Wei 2 ; Wan, Yaya 2 ; Zhou, Pengjuan 2 ; Tang, Dong 1 ;
作者机构： 1.Quzhou Coll Technol, Dept Chem & Mat Engn, Quzhou 324002, Peoples R China
2.Ningxia Acad Agr & Forestry Sci, Agr Resource & Environm Inst, Ningxia Ctr Agr Organ Synth, Yinchuan 750004, Peoples R China
关键词： Imidazoheterocycles; Iodobenzen diacetate; Halogenation; Tetrabutylammonium halide; 3-Haloimidazopyridine
期刊名称：TETRAHEDRON LETTERS （ 影响因子：1.5； 五年影响因子：1.6 ）
ISSN： 0040-4039
年卷期： 2024 年 144 卷
页码：
收录情况： SCI
摘要： An efficient and environment-friendly method for the synthesis of 3-haloimidazopyridine derivatives has developed by the halogenation of imidazoheterocycles with Bu4NX (X = Cl, Br, and I) using iodobenzene diacetate as oxidant in ethanol. This protocol features with short reaction time for bromination and iodination, ambient temperature, facile operation, good functional group tolerance and good yeilds.
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