Effects of dietary glutathione on the growth performance, skin mucus antioxidant capacity, and immune responses of juvenile taimen Hucho taimen
文献类型： 外文期刊
作者： Wang, Chang'an 1 ; Lu, Shaoxia 1 ; Fan, Ze 1 ; Han, Shicheng 1 ; Liu, Yang 1 ; Jiang, Haibo 2 ; Liu, Hongbai 1 ;
作者机构： 1.Chinese Acad Fishery Sci, Heilongjiang River Fisheries Res Inst, Key Lab Aquat Anim Dis & Immune Technol Heilongji, 232 Hesong St, Harbin 150070, Peoples R China
2.Guizhou Univ, Coll Anim Sci, Guiyang 550025, Peoples R China
关键词： Glutathione; Feed additives; Skin inflammation; Gene expression; Hucho taimen
期刊名称：AQUACULTURE INTERNATIONAL （ 影响因子：2.953； 五年影响因子：2.94 ）
ISSN： 0967-6120
年卷期：
页码：
收录情况： SCI
摘要： A 49-day feeding trial was conducted to examine the effects of dietary glutathione on growth performance, skin antioxidant capacity, immune responses, and gene expression in juvenile taimen (Hucho taimen). The experimental fish had a mean initial weight of 5.36 +/- 0.13 g and were fed diets (approximately crude protein 460 g/kg, gross energy 22 MJ/kg) containing graded amounts of glutathione (0-control, 100, 200, 400, and 800 mg/kg). Each group had 3 replicates with 500 fish per tank (500 L). Fish were fed four times daily until evident satiation. After the feeding trial, 60 fish from each tank were challenged with lipopolysaccharide for 7 days, and the skin mucus antibacterial activity, antioxidant ability, and skin gene expression were also determined. The weight gain (WG, 3642.33-3843.67 g) and survival rate (SR, 93.07-94.19%) were all significantly improved in fish fed dietary glutathione (100-800 mg/kg) compared with the control group (WG, 3414.30 g; SR, 90.61%) (P < 0.05). After a 7-day lipopolysaccharide (3.00 mg/kg body weight) challenge, compared with the control group, dietary glutathione (100-800 mg/kg) significantly increased skin mucus protein, lysozyme activity (LZM, 2.67-2.74 U/mg; control, 2.11 U/mg), alkaline phosphate activity (ALP, 5.09-5.34 U/L; control, 4.50 U/L), minimal inhibitory concentration (MIC, 100-200 mu L/mL; control, > 200 mu L/mL), and antimicrobial activity (7.72-9.11 mm; control, 7.19 mm) (P < 0.05). Furthermore, dietary glutathione (100-800 mg/kg) also improved skin mucus antioxidant capacity and superoxide dismutase (SOD, 9.45-9.52 U/L; control, 7.51 U/L), and glutathione peroxidase (GSH-px, 9.68-10.11 U/L; control, 8.68 U/L) was significantly higher (P < 0.05), whereas the malondialdehyde (MDA, 0.18-0.20 nmol/L; control, 0.23 nmol/L) concentration was lower (P < 0.05). Additionally, dietary glutathione (100-800 mg/kg) significantly decreased the expression levels of skin tumor necrosis factor (TNF-alpha), interleukin 1 beta (IL-1 beta), interleukin 6 (IL-6), and interleukin 8 (IL-8), but increased the expression levels of interleukin 10 (IL-10) and nuclear factor-kappa-B inhibitor alpha-like (I kappa B alpha). In conclusion, dietary glutathione (100-800 mg/kg) improved the growth performance and decreased the lipopolysaccharide-induced skin inflammatory response, indicating that glutathione has the potential for anti-inflammatory effects on juvenile H. taimen.
- 相关文献
作者其他论文 更多>>
-
Structure dependence of the enhanced sulfur tolerance of core-shell CoMn oxides for benzene oxidation: Discrepant sulfur species and less affected reactant activation
作者：Liu, Yang;Cheng, Lin;Zhang, Di;Zhan, Jingjing;Shan, Jiajia;Zhou, Hao;Yi, Xianliang;Li, Zhonghong;Shen, Xudong
关键词：VOCs; Catalytic oxidation; Manganese oxide; Cobalt decoration; Sulfur resistance
-
Surviving the heat: The homeostatic regulation mechanism of endangered Brachymystax tsinlingensis
作者：Wang, Zhenlu;Liu, Peng;Wang, Yizhou;Jiang, Haibo;Shao, Jian;Ye, Huan;Zhou, Qiong;Lin, Shaoqing
关键词：Brachymystax tsinlingensis; Heat stress; Homeostasis; Transcriptome
-
Single atom Z-scheme heterostructure catalysts of photosensitive metal-organic nanorings and graphite-C3N4 for visible light-driven hydrogen production
作者：Hou, Chao-Ping;Liu, Yang;Liu, Jia-Xin;Li, Xin-Ao;Liang, Zi-Zhan;Liu, Jun-Min;Hou, Chao-Ping;Tan, Li-Lin
关键词：Metal-organic nanoring; Z-scheme heterojunction; Single-atom catalyst; Photocatalytic hydrogen evolution
-
Exploring Disparities in Gill Physiological Responses to NaHCO3-Induced Habitat Stress in Triploid and Diploid Crucian Carp (Carassius auratus): A Comprehensive Investigation Through Multi-Omics and Biochemical Analyses
作者：Han, Shicheng;Han, Lin;Yuan, Fangying;Liu, Wenzhi;Jin, Xiaofeng;Sun, Yanchun;Han, Lin;Liu, Wenzhi;Yuan, Fangying;Wang, Jing;Jin, Xiaofeng
关键词：crucian carp (
Carassius auratus ); diploid; triploid; carbonate alkalinity; metabolomics; transcriptomics -
Spatial-temporal distribution of phytoplankton HAB species and contamination status of oyster toxins under intensive oyster farming in Jiangmen coasts, the South China Sea
作者：Zou, Jian;Xiao, Yayuan;Su, Jiaqi;Wu, Peng;Wang, Teng;Lin, Lin;Li, Chunhou;Liu, Yu;Liu, Yong;Zou, Jian;Xiao, Yayuan;Wu, Peng;Wang, Teng;Liu, Yong;Liu, Yang;Wang, Teng;Liu, Yu;Liu, Yong
关键词：HAB species of phytoplankton; Alexandrium pacificum; Paralytic shellfish poisoning; Diarrhetic shellfish poisoning; Jiangmen oyster farming area
-
Multi-omics-based study on metabolic-physiological response to heat stress in rainbow trout (Oncorhynchus mykiss)
作者：Yang, Yang;Wu, Song;Sun, Yanchun;Han, Shicheng;Liu, Yingjie;Liu, Wenzhi;Han, Lin;Yuan, Fangying;Wang, Jing
关键词：Rainbow trout; Heat stress; Multi-omics; Adaptive strategies; Inflammation response
-
Increases in forest carbon stocks of up to 32% by 2100 across the subalpine forests of the Tibetan Plateau
作者：Li, Ting;Wang, Huan;Wang, Jicheng;Li, Xiaorui;Wang, Qi;Wang, Qi;Liao, Zhanmang;Luo, Peng;Luo, Peng;Lai, Changhong;Liu, Yang;Jian, Yi
关键词：Climate velocity; Forest recovery; Growth; Mortality; Mountain forests; Stand age
