您好，欢迎访问江苏省农业科学院 机构知识库！
江苏省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Quantitative Analysis of Fungal Contamination of Different Herbal Medicines in China

文献类型： 外文期刊

作者： Wang, Gang 1 ; Jiao, Mingyue 1 ; Hu, Junqiang 2 ; Xun, Yiren 1 ; Chen, Longyun 1 ; Qiu, Jianbo 2 ; Ji, Fang 2 ; Lee, Yin-Won 4 ; Shi, Jianrong 2 ; Xu, Jianhong 1 ;

作者机构： 1.Jiangsu Univ, Sch Food & Biol Engn, Zhenjiang 212013, Peoples R China

2.Jiangsu Acad Agr Sci, Minist Agr & Rural Affairs, Inst Food Safety & Nutr, Minist Sci & Technol,Collaborat Innovat Ctr Modern, Nanjing 210014, Peoples R China

3.Nanjing Agr Univ, Coll Life Sci, Key Lab Agr Environm Microbiol, Minist Agr, Nanjing 210095, Peoples R China

4.Seoul Natl Univ, Dept Agr Biotechnol, Seoul 08826, South Korea

关键词： mycotoxin; phytopathogenic fungi; herbal medicine; ITS sequencing; RT-qPCR; LC-MS/MS

期刊名称：TOXINS （ 影响因子：4.2； 五年影响因子：4.7 ）

ISSN：

年卷期： 2024 年 16 卷 5 期

页码：

收录情况： SCI

摘要： Herbal medicines are widely used for clinical purposes worldwide. These herbs are susceptible to phytopathogenic fungal invasion during the culturing, harvesting, storage, and processing stages. The threat of fungal and mycotoxin contamination requires the evaluation of the health risks associated with these herbal medicines. In this study, we collected 138 samples of 23 commonly used herbs from 20 regions in China, from which we isolated a total of 200 phytopathogenic fungi. Through morphological observation and ITS sequencing, 173 fungal isolates were identified and classified into 24 genera, of which the predominant genera were Fusarium (27.74%) and Alternaria (20.81%), followed by Epicoccum (11.56%), Nigrospora (7.51%), and Trichocladium (6.84%). Quantitative analysis of the abundance of both Fusarium and Alternaria in herbal medicines via RT-qPCR revealed that the most abundant fungi were found on the herb Taraxacum mongolicum, reaching 300,000 copies/mu L for Fusarium and 700 copies/mu L for Alternaria. The in vitro mycotoxin productivities of the isolated Fusarium and Alternaria strains were evaluated by using liquid chromatography-tandem mass spectrometry (LC-MS/MS), and it was found that the Fusarium species mainly produced the acetyl forms of deoxynivalenol, while Alternaria species mainly produced altertoxins. These findings revealed widely distributed fungal contamination in herbal medicines and thus raise concerns for the sake of the quality and safety of herbal medicines.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：江苏省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台