您好，欢迎访问中国水产科学研究院 机构知识库！
中国水产科学研究院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Homologues of sox8 and sox10 in the orange-spotted grouper Epinephelus coioides: Sequences, expression patterns, and their effects on cyp19a1a promoter activities in vitro

文献类型： 外文期刊

作者： Liu, Qiongyou 1 ; Lu, Huijie 1 ; Zhang, Lihong 1 ; Xie, Jun 2 ; Shen, Wenying 3 ; Zhang, Weimin 1 ;

作者机构： 1.Sun Yat Sen Univ, Sch Life Sci, Inst Aquat Econ Anim, State Key Lab Biocontrol, Guangzhou 510275, Guangdong, Peoples R China

2.Chinese Acad Fishery Sci, Key Lab Trop & Subtrop Fishery Resource Applicat, Minist Agr, Pearl River Fishery Res Inst, Guangzhou 510380, Guangdong, Peoples R China

3.Univ Shaoxing, Sch Life Sci, Shaoxing 312000, Peoples R China

关键词： Cyp19a1a promoter;Orange-spotted grouper Epinephelus coioides;Sox10a;Sox8a;Transcriptional regulation

期刊名称：COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY （ 影响因子：2.231； 五年影响因子：2.215 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Sox8 and Sox10 are members of group E Sox proteins involved in a wide range of developmental processes including sex determination and neurogenesis in vertebrates. The orange-spotted grouper sox8a and sox10a homologues were isolated and characterized in the present study. Both sox8a and sox10a genes contain three exons and two introns, and encode putative proteins with typical structures of group E Sox. Sox8a was expressed in diverse tissues including the central nervous system and some peripheral tissues. In contrast, sox10a mRNA was detected primarily in the central nervous system. During embryogenesis, sox8a mRNA seemed to bede novo synthesized in the embryos from otic vesicle stage. However, sox10a mRNA was only detectable in juvenile fish 35. days post hatching and thereafter. The mRNA levels of sox8a in the gonads were not significantly different among ovarian developmental stages but increased in the testis. In vitro transfection assays showed that the Sox10a but not Sox8a up-regulated cyp19a1a promoter activities. Taken together, these results suggested that the sox8a may play roles in diverse tissues and during embryogenesis, whereas sox10a may be mainly involved in the neural regulation of juvenile and adult fish, and that certain Sox homologues may regulate the orange-spotted grouper cyp19a1a promoter.

  • 相关文献

[1]Effects of prey color, wall color and water color on food ingestion of larval orange-spotted grouper Epinephelus coioides (Hamilton, 1822). Zhang, Jiasong,Guo, Huayang,Ma, Zhenhua,Jiang, Shigui,Wu, Kaichang,Li, Youning,Zhang, Jiasong,Qin, Jian G..

[2]Bioinformatic Analyses of CCCH-Zinc Finger Family in Zebrafish (Danio rerio). Shui, Yan,Xu, Zeng-Hong,Zhou, Xin,Zhou, Xin. 2014

作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国水产科学研究院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台