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Chiral discrimination and enantiomeric composition analysis of quinine and quinidine based on paper substrate room temperature phosphorescence

文献类型: 外文期刊

作者: Qin, Guojie 2 ; Wei, Yanli 1 ; Kang, Hui 1 ; Dong, Chuan 1 ;

作者机构: 1.Shanxi Univ, Sch Chem & Chem Engn, Res Ctr Environm Sci & Engn, Taiyuan 030006, Peoples R China

2.Shanxi Univ, Shanxi Acad Agr Sci, Inst Hort, Taiyuan 030031, Peoples R China

期刊名称:ANALYTICAL METHODS ( 影响因子:2.896; 五年影响因子:2.716 )

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收录情况: SCI

摘要: Based on paper substrate room temperature phosphorescence, the chiral discrimination of quinine and quinidine was achieved using Whatman No. 40 filter paper as the substrate and Pb(Ac)2 as the heavy atom perturber. The phosphorescence lifetime differences between quinine and quinidine increased from 4.45% to 27.90% upon addition of (+)-tartaric acid as the chiral modifier. This provided a rapid and simple method for the determination of the enantiomeric composition of quinine and quinidine.

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