文献类型: 外文期刊
作者: Wu, Haibo 1 ; Lu, Rufeng; Peng, Xiaorong 1 ; Xu, Lihua; Cheng, Linfang 1 ; Lu, Xiangyun 1 ; Jin, Changzhong 1 ; Xie 1 ;
作者机构: 1.Zhejiang Univ, State Key Lab Diag & Treatment Infect Dis, Collaborat Innovat Ctr Diag & Treatment Infect Di, Affiliated Hosp1,Sch Med, Hangzhou 310003, Zhejiang, Peoples R China
2.Zhejiang Univ, State Key Lab Diag & Treatment Infect Dis, Collaborat Innovat Ctr Diag & Treatment Infect Di, Affiliated Hosp1,Sch
关键词: Avian influenza virus;H5N6;Virus reassortment;Poultry;China
期刊名称:INFECTION GENETICS AND EVOLUTION ( 影响因子:3.342; 五年影响因子:3.188 )
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收录情况: SCI
摘要: We characterized two novel highly pathogenic H5N6 influenza viruses isolated from Chinese poultry in 2013. Genomic analysis showed that both isolates were reassortants, and derived their genes from H5 and H6 subtype viruses found in poultry in China. The virulence of the two isolates was examined in chickens and mice, and both isolates were found to be highly pathogenic in chickens and only moderately virulent for mice. Our results show that continued circulation of these viruses could endanger both avian species and humans. (C) 2015 Elsevier B.V. All rights reserved.
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